Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Background— C-reactive protein (CRP) is a heritable marker of chronic inflammation that is
strongly associated with cardiovascular disease. We sought to identify genetic variants that …

… receptor(s) and/or decrease its secretion, perhaps by decreasing its affinity for the protease(s)
… might be the result of the presence of the A antigen on its receptor(s) and/or protease(s). …

… Here we introduce such functionalities in Cs 2 NaInCl 6 by codoping Sb 3+ (s-electron … it
has two s-electrons (5s 2 ) in the outermost orbitals. Upon excitation, one of the s-electrons goes …

Purpose Ganitumab is a fully human monoclonal antibody against type-1 insulin-like growth
factor receptor (IGF1R). An open-label phase II study was conducted to evaluate the efficacy …

Introduction We assessed the Aurora A kinase inhibitor, alisertib, plus paclitaxel (henceforth
referred to as alisertib/paclitaxel) as second-line treatment for SCLC. Methods In this double-…

… Total RNA was isolated using RNAeasy technology on a Biorobot 8000 workstation and
DNase treated according to the manufacturer’s protocol (Qiagen). The purity and yield of the …

… (1), where S V is the final vulnerability score, S D is the gear density score, S R is the IUCN
Red List score and S L is the literature-based evidence score)… (1) S V = S D × S R × S L …

… Louis, MO) and cycling parameters of an initial 95C for 2 min and then 40 cycles of 95C for
20 s, 58C for 20 s, and 76C for 20 s. Data were analyzed using SDS 1.7 (Applied Biosystems) …

… Suzuki, and S. Badola are former employees of and are shareholders in Amgen Inc. HL
Kindler is an advisor for Amgen Inc. CS Fuchs is an advisor for Amgen Inc., ImClone Systems, …