Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker

PP Bradley, DA Priebat, RD Christensen… - Journal of investigative …, 1982 - Elsevier
We examined the hypothesis that myeloperoxidase (MPO), a plentiful constituent of neutrophils,
might seve as a marker for tissue neutrophil content. To completely extract MPO from …

[HTML][HTML] Niraparib maintenance therapy in platinum-sensitive, recurrent ovarian cancer

…, C Marth, R Mądry, RD Christensen… - … England Journal of …, 2016 - Mass Medical Soc
Background Niraparib is an oral poly(adenosine diphosphate [ADP]–ribose) polymerase (PARP)
1/2 inhibitor that has shown clinical activity in patients with ovarian cancer. We sought …

Cellular and extracellular myeloperoxidase in pyogenic inflammation

PP Bradley, RD Christensen, G Rothstein - 1982 - ashpublications.org
We explored the effect of in vitro phagocytosis and in vivo inflammation on the MPO content
of functioning neutrophils and on the ability of these cells to export active MPO into the …

[HTML][HTML] Erythropoietin and erythropoietin receptor in the developing human central nervous system

SE Juul, DK Anderson, Y Li, RD Christensen - Pediatric research, 1998 - nature.com
We have previously shown the presence of erythropoietin (Epo) within the spinal fluid of
normal preterm and term infants, and the presence of Epo receptor (Epo-R) in the spinal cords …

Reference ranges for hematocrit and blood hemoglobin concentration during the neonatal period: data from a multihospital health care system

…, E Henry, SE Wiedmeier, RD Christensen - Pediatrics, 2009 - publications.aap.org
OBJECTIVE. “Reference ranges” are developed when it is impossible or inappropriate to
establish “normal ranges” by drawing blood on healthy normal volunteers. Reference ranges …

Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus

SE Juul, AT Yachnis, RD Christensen - Early human development, 1998 - Elsevier
Objective: Erythropoietin receptors (Epo-R) have been demonstrated on several nonhematopoietic
cell types in animal models and in cell culture. Our objective was to determine the …

Identifying patients, on the first day of life, at high-risk of developing parenteral nutrition-associated liver disease

RD Christensen, E Henry, SE Wiedmeier… - Journal of …, 2007 - nature.com
Background: Prolonged use of parenteral nutrition (PN) in neonates can lead to parenteral
nutrition-associated liver disease (PNALD), manifested by elevated direct bilirubin …

Platelet reference ranges for neonates, defined using data from over 47 000 patients in a multihospital healthcare system

…, E Henry, MC Sola-Visner, RD Christensen - Journal of …, 2009 - nature.com
Objective: Identifying a platelet count as abnormal (thrombocytopenia or thrombocytosis) can
facilitate recognizing various disease states. However, the published reference ranges for …

Thrombocytopenia among extremely low birth weight neonates: data from a multihospital healthcare system

RD Christensen, E Henry, SE Wiedmeier… - Journal of …, 2006 - nature.com
Objectives: Thrombocytopenia is common in neonatal intensive care units (NICU), with 18
to 35% of patients developing this problem before hospital discharge. It might be even more …

Expected ranges for blood neutrophil concentrations of neonates: the Manroe and Mouzinho charts revisited

…, E Henry, J Jopling, RD Christensen - Journal of …, 2008 - nature.com
Background: Upper and lower reference limits for blood neutrophil concentrations of
neonates were reported by Manroe, Rosenfeld and co-workers in 1979 and by Mouzinho, …