Systematic reviews are difficult to keep up to date, but failure to do so leads to a decay in
review currency, accuracy, and utility. We are developing a novel approach to systematic …

The biomedical research complex has been estimated to consume almost a quarter of a trillion
US dollars every year. Unfortunately, evidence suggests that a high proportion of this sum …

… We checked whether the results were unavailable because of the result’s P value, magnitude,
or direction. We considered the risk of bias due to missing results if one specified outcome …

Aims To identify the characteristics, treatment, and outcomes of contemporary patients with
valvular heart disease (VHD) in Europe, and to examine adherence to guidelines. Methods …

Importance Severe pneumonia with hyperinflammation and elevated interleukin-6 is a common
presentation of coronavirus disease 2019 (COVID-19). Objective To determine whether …

… using a backward procedure with a threshold of P=0.05, except for the … P<0.25 were entered
into a multivariable Cox model and selected by a backward procedure with a threshold of P=…

… Twenty-five patients in each group (P=0.92) had severe adverse events; there were 44 events
in the azathioprine group and 45 in the rituximab group. Eight patients in the azathioprine …

Adequate reporting of randomized, controlled trials (RCTs) is necessary to allow accurate
critical appraisal of the validity and applicability of the results. The CONSORT (Consolidated …

… Variables with P < 0.25 were entered in a multivariable logistic model and were selected
using a backward procedure with a threshold of P = 0.05. An internal validation of the model …

… P Ravaud2, … % in Eastern, and 2.9% in Mediterranean Europe (p = 0.34). IE occurred on
native valves in … was 10.4% and 15.6% among the patients who underwent surgery (p = 0.42). …