ContextThe treatment of juvenile idiopathic arthritis (JIA) has changed markedly in the last
15 years. Many children with JIA are not treated by pediatric rheumatologists.ObjectiveTo …

… Hashkes PJ … Hashkes PJ … Hashkes PJ …

Background Polyarteritis nodosa is a systemic necrotizing vasculitis with a pathogenesis
that is poorly understood. We identified six families with multiple cases of systemic and …

Background Some children with juvenile idiopathic arthritis either do not respond, or are
intolerant to, treatment with disease-modifying antirheumatic drugs, including anti-tumour …

The treatment of juvenile idiopathic arthritis (JIA) has been revolutionized by the use of
novel biologic agents that have much improved patients' short-term and, according to early …

BACKGROUND. Monogenic IFN–mediated autoinflammatory diseases present in infancy with
systemic inflammation, an IFN response gene signature, inflammatory organ damage, and …

Background Familial Mediterranean fever, mevalonate kinase deficiency (also known as the
hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor receptor–associated …

Objective To determine whether aggressive treatment initiated early in the course of rheumatoid
factor (RF)–positive or RF‐negative polyarticular juvenile idiopathic arthritis (JIA) can …

Chinese translation This article has been corrected. The original version (PDF) is appended
to this article as a Supplement . Background: Currently, there is no proven alternative …

Objective Juvenile fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder
in children and adolescents for which there are no evidence‐based treatments. The …