[HTML][HTML] Mechanism of action of colchicine in the treatment of gout
N Dalbeth, TJ Lauterio, HR Wolfe - Clinical therapeutics, 2014 - Elsevier
Purpose The aims of this article were to systematically review the literature about the
mechanism of action of colchicine in the multimodal pathology of acute inflammation associated …
mechanism of action of colchicine in the multimodal pathology of acute inflammation associated …
Mechanisms of inflammation in gout
N Dalbeth, DO Haskard - Rheumatology, 2005 - academic.oup.com
The clinical manifestations of gout are due to interactions between monosodium urate (MSU)
crystals and local tissues. This review article outlines recent advances in the understanding …
crystals and local tissues. This review article outlines recent advances in the understanding …
[HTML][HTML] A review of uric acid, crystal deposition disease, and gout
F Perez-Ruiz, N Dalbeth, T Bardin - Advances in therapy, 2015 - Springer
There has been increased interest in gout in both academic and clinical practice settings.
Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in …
Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in …
2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to …
Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia, which …
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia, which …
2020 American College of Rheumatology guideline for the management of gout
JD FitzGerald, N Dalbeth, T Mikuls… - Arthritis & …, 2020 - Wiley Online Library
… Taylor WJ, Brown M, Aati O, Weatherall M, Dalbeth N. Do patient preferences for core
outcome domains for chronic gout studies support the validity of composite response criteria? …
outcome domains for chronic gout studies support the validity of composite response criteria? …
[PDF][PDF] 2015 gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
T Neogi, TLTA Jansen, N Dalbeth… - Arthritis & …, 2015 - Wiley Online Library
Objective Existing criteria for the classification of gout have suboptimal sensitivity and/or
specificity, and were developed at a time when advanced imaging was not available. The …
specificity, and were developed at a time when advanced imaging was not available. The …
2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis
In response to a request for proposal from the American College of Rheumatology (ACR), our
group was charged with developing nonpharmacologic and pharmacologic guidelines for …
group was charged with developing nonpharmacologic and pharmacologic guidelines for …
[HTML][HTML] Effects of allopurinol on the progression of chronic kidney disease
Background Elevated serum urate levels are associated with progression of chronic kidney
disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the …
disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the …
Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol
…, J Drake, C Frampton, N Dalbeth - Arthritis & …, 2012 - Wiley Online Library
Objective Allopurinol is the most commonly used urate‐lowering therapy in gout. Allopurinol
hypersensitivity syndrome (AHS) is a rare but potentially fatal adverse event. Dosing …
hypersensitivity syndrome (AHS) is a rare but potentially fatal adverse event. Dosing …
CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation
N Dalbeth, R Gundle, RJO Davies, YC Lee… - The Journal of …, 2004 - journals.aai.org
… The results shown are representative of a total of 19 experiments performed using cells
from synovial fluid (n = 7), synovial tissue (n = 5), and pleural fluid (n = 5). Very similar results …
from synovial fluid (n = 7), synovial tissue (n = 5), and pleural fluid (n = 5). Very similar results …