Biologics have been a key component of severe asthma treatment, and there are currently
biologics available that target IgE, IL-5, IL-4/IL-13, and TSLP. Randomized controlled trials …

Dietary flavonoid intake has been reported to be inversely associated with the incidence of
coronary artery disease. To clarify the possible role of tea flavonoids in the prevention of …

Basophils are thought to play pivotal roles in allergic inflammation through rapid release of
chemical mediators in addition to sustained production of Th2 cytokines, including IL-4. A …

… to recognize the virulent strain M. tuberculosis H37Rv and the vaccine strain M. bovis Bacille
… We next fractionated components of M. bovis BCG using lipophilic and hydrophilic solvents, …

… The plate was left at room temperature until reaching the desired extinction, and the reaction
was terminated with 50 μl of 1 M sulfuric acid solution. The optimal density was read at 490/…

Orosomucoid like 3 (ORMDL3) has been strongly linked with asthma in genetic association
studies, but its function in asthma is unknown. We demonstrate that in mice ORMDL3 is an …

Immunoglobulin (Ig)A is the most abundant immunoglobulin in humans, and in the airway
mucosa secretory IgA (sIgA) plays a pivotal role in first-line defense against invading …

Orosomucoid-like (ORMDL) 3 has been strongly linked with asthma in genetic association
studies. Because allergen challenge induces lung ORMDL3 expression in wild-type mice, we …

… Effects of fish oil fatty acids on low density lipoprotein size, oxidizability, and uptake by
macrophages Michio Suzukawa, Mavis Abbey,' Peter RC Howe, and Paul J. Nestel CSIRO, …

Objective. Postmarketing surveillance (PMS) was conducted evaluating safety and effectiveness
of etanercept (ETN; Enbrel ® ) in Japan, following all patients with rheumatoid arthritis (…