Country as the primary risk factor for renal amyloidosis in familial Mediterranean fever
…, T Sarkisian, M Medlej‐Hashim, M Tunca… - Arthritis & …, 2007 - Wiley Online Library
Objective Familial Mediterranean fever (FMF), the prototype of autoinflammatory disorders,
is caused by recessive mutations in the MEFV gene. Some FMF patients develop renal …
is caused by recessive mutations in the MEFV gene. Some FMF patients develop renal …
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
…, B Copin, E Cochet, M Medlej-Hashim… - Science translational …, 2016 - science.org
Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome
complex that drives the cleavage and secretion of interleukin-1β (IL-1β). Mutations in …
complex that drives the cleavage and secretion of interleukin-1β (IL-1β). Mutations in …
[HTML][HTML] Microfibrillar-associated protein 4 in health and disease
R Kanaan, M Medlej-Hashim, R Jounblat, B Pilecki… - Matrix Biology, 2022 - Elsevier
Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein belonging to
the fibrinogen-related domain family. It has been localized to elastic fiber-rich regions in …
the fibrinogen-related domain family. It has been localized to elastic fiber-rich regions in …
[HTML][HTML] Vibratory Urticaria Associated with a Missense Variant in ADGRE2
…, A Mégarbané, M Medlej-Hashim… - … England Journal of …, 2016 - Mass Medical Soc
<p id="p001">Patients with autosomal dominant vibratory urticaria have localized hives and
systemic manifestations in response to dermal vibration, with coincident degranulation of …
systemic manifestations in response to dermal vibration, with coincident degranulation of …
Familial Mediterranean Fever (FMF): from diagnosis to treatment
M Medlej-Hashim, J Loiselet, G Lefranc… - Cahiers d'études et de …, 2004 - jle.com
… high sedimentation rate and white blood cell count, but during and immediately after crises,
diminished albumin concentrations and elevated fibrinogen, C-reactive protein, β2 and α2 M …
diminished albumin concentrations and elevated fibrinogen, C-reactive protein, β2 and α2 M …
[HTML][HTML] Amyloidosis in familial Mediterranean fever patients: correlation with MEFV genotype and SAA1 and MICA polymorphisms effects
M Medlej-Hashim, V Delague, E Chouery, N Salem… - BMC medical …, 2004 - Springer
… Myrna Medlej-Hashim looked for the patients, tested the SAA1 and MICA alleles and wrote
the article. Valérie Delague helped in the recruitment of Lebanese FMF patients and MICA …
the article. Valérie Delague helped in the recruitment of Lebanese FMF patients and MICA …
Familial Mediterranean fever in the Syrian population: gene mutation frequencies, carrier rates and phenotype–genotype correlation
…, S Al-Cheikh, M El-Khateeb, M Medlej-Hashim… - European journal of …, 2006 - Elsevier
BACKGROUND: Familial Mediterranean fever (FMF) is an autosomal recessive disease
mainly affecting particularly Arabs, Non-Ashkenazi Jews, Armenians, and Turks. It is an …
mainly affecting particularly Arabs, Non-Ashkenazi Jews, Armenians, and Turks. It is an …
Familial Mediterranean fever in Lebanon: mutation spectrum, evidence for cases in Maronites, Greek orthodoxes, Greek catholics, Syriacs and Chiites and for an …
…, E Chouery, C Pêcheux, M Medlej-Hashim… - European Journal of …, 2001 - nature.com
… 7 Pras M: Clinical differences between North African and Iraqi Jews with FMF. Am J Med
Genet 1998; 75: 216–219. 8 Touitou I, Ben-Chetrit E, Notrnicola C et al: Familial Mediterranean …
Genet 1998; 75: 216–219. 8 Touitou I, Ben-Chetrit E, Notrnicola C et al: Familial Mediterranean …
Familial Mediterranean fever (FMF) in Lebanon and Jordan: a population genetics study and report of three novel mutations
M Medlej-Hashim, JL Serre, S Corbani, O Saab… - European journal of …, 2005 - Elsevier
Familial Mediterranean fever (FMF) is an autosomal recessive disease mostly frequent in
Mediterranean populations. Over 50 mutations have been identified in the gene responsible for …
Mediterranean populations. Over 50 mutations have been identified in the gene responsible for …
Ex vivo PBMC cytokine profile in familial Mediterranean fever patients: Involvement of IL-1β, IL-1α and Th17-associated cytokines and decrease of Th1 and Th2 …
…, N Salem, E Chouery, A Megarbane, M Medlej-Hashim… - Cytokine, 2014 - Elsevier
In order to clarify the inflammatory mechanism underlying familial Mediterranean fever (FMF),
we aimed to evaluate the ex vivo cytokine profile of FMF patients during acute attacks and …
we aimed to evaluate the ex vivo cytokine profile of FMF patients during acute attacks and …