Objective Familial Mediterranean fever (FMF), the prototype of autoinflammatory disorders,
is caused by recessive mutations in the MEFV gene. Some FMF patients develop renal …

Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome
complex that drives the cleavage and secretion of interleukin-1β (IL-1β). Mutations in …

Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein belonging to
the fibrinogen-related domain family. It has been localized to elastic fiber-rich regions in …

<p id="p001">Patients with autosomal dominant vibratory urticaria have localized hives and
systemic manifestations in response to dermal vibration, with coincident degranulation of …

… high sedimentation rate and white blood cell count, but during and immediately after crises,
diminished albumin concentrations and elevated fibrinogen, C-reactive protein, β2 and α2 M …

… Myrna Medlej-Hashim looked for the patients, tested the SAA1 and MICA alleles and wrote
the article. Valérie Delague helped in the recruitment of Lebanese FMF patients and MICA …

BACKGROUND: Familial Mediterranean fever (FMF) is an autosomal recessive disease
mainly affecting particularly Arabs, Non-Ashkenazi Jews, Armenians, and Turks. It is an …

… 7 Pras M: Clinical differences between North African and Iraqi Jews with FMF. Am J Med
Genet 1998; 75: 216–219. 8 Touitou I, Ben-Chetrit E, Notrnicola C et al: Familial Mediterranean …

Familial Mediterranean fever (FMF) is an autosomal recessive disease mostly frequent in
Mediterranean populations. Over 50 mutations have been identified in the gene responsible for …

In order to clarify the inflammatory mechanism underlying familial Mediterranean fever (FMF),
we aimed to evaluate the ex vivo cytokine profile of FMF patients during acute attacks and …