Objective The objective of this study was to evaluate the efficacy and safety of tramadol in
treating the pain of diabetic neuropathy. Background The pain of diabetic neuropathy is a …

OBJECTIVE: Binge eating disorder is associated with obesity. Topiramate is an antiepileptic
agent associated with weight loss. The objective of this study was to evaluate topiramate in …

PURPOSE: To evaluate the efficacy and safety of a combination analgesic tablet (37.5 mg
tramadol/325 mg acetaminophen) for the treatment of fibromyalgia pain. METHODS: This 91-…

An outpatient, randomized, double-blind, placebo-controlled clinical trial was conducted to
evaluate the efficacy and safety of tramadol in the treatment of the pain of fibromyalgia …

Background More than a third of patients with epilepsy are treatment resistant, and thus new,
more effective therapies to achieve seizure freedom are needed. Cenobamate (YKP3089), …

… Schnitzer TJ, Gray WL, Paster RZ, Kamin M. Efficacy of tramadol in treatment of chronic
low … Bennett RM, Kamin M, Karim R, Rosenthal N. Tramadol and acetaminophen combination …

OBJECTIVE: To evaluate the analgesic efficacy and safety of tramadol 37.5 mg/acetaminophen
325 mg (tramadol/APAP) combination tablets for treatment of chronic low back pain (LBP)…

Objective To evaluate the efficacy and safety of tramadol in the treatment of chronic low back
pain. Methods A 3 phase trial:(1) a washout/screening phase;(2) a 3 week, open label, run-…

Objective: The objective of this study was to evaluate the efficacy and safety of tramadol in a
6-month open extension following a 6-week double-blind randomized trial. Research design …

Objective During the development of cenobamate, an antiseizure medication (ASM) for
focal seizures, three cases of drug reaction with eosinophilia and systemic symptoms (DRESS) …