Systemic lupus erythematosus is a disease of immune dysregulation that strikes approximately
1 in 2000 individuals. The usual patient is a young woman of child-bearing age; however, …

Objectives To validate the previously proposed classification criteria for Henoch–Schönlein
purpura (HSP), childhood polyarteritis nodosa (c-PAN), c-Wegener granulomatosis (c-WG) …

Objective To provide updated guidelines for pharmacologic management of juvenile
idiopathic arthritis (JIA), focusing on treatment of oligoarthritis, temporomandibular joint (TMJ) …

… HI Brunner and MS Klein-Gitelman made substantial contributions to discussing the content
of the article. All authors took part in writing, reviewing and editing the manuscript before …

Background Tofacitinib is an oral Janus kinase inhibitor. This trial assessed the efficacy and
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …

A combined forward and reverse genetic approach was undertaken to test the candidacy of
IRAK1 (interleukin-1 receptor associated kinase-1) as an X chromosome-encoded risk factor …

Objective To obtain international consensus around processes that support the delivery of
high‐quality care to patients with childhood‐onset systemic lupus erythematosus (SLE) based …

Objective To describe the character and composition of the 2015 US adult rheumatology
workforce, evaluate workforce trends, and project supply and demand for clinical rheumatology …

Objective Autoimmune encephalitis (AE) is an important and treatable cause of acute
encephalitis. Diagnosis of AE in a developing child is challenging because of overlap in clinical …

Objective To assess the reliability and validity of the Disease Activity Score (DAS), an instrument
used to evaluate children with juvenile dermatomyositis (JDM). Methods Psychometric …