BACKGROUND Micropapillary bladder carcinoma is a rare variant of urothelial carcinoma.
To improve understanding of this disease, the authors performed a retrospective review of …

Current therapeutic development in amyotrophic lateral sclerosis (ALS) relies on individual
randomized clinical trials to test a specific investigational product in a single patient …

Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …

Purpose Fludarabine and cyclophosphamide (FC), which are active in treatment of chronic
lymphocytic leukemia (CLL), are synergistic with the monoclonal antibody rituximab in vitro in …

Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …

Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in
patients not admitted to hospital, but effectiveness in high-risk individuals is unknown. We …

Background: Although research focused on African Americans with mental illness has been
increasing, few researchers have addressed gender and age differences in beliefs, attitudes…

Longitudinal studies often include multiple, repeated measurements of each patient’s status
or outcome to assess differences in outcomes or in the rate of recovery or decline over time. …

Importance Platelets represent a potential therapeutic target for improved clinical outcomes
in patients with COVID-19. Objective To evaluate the benefits and risks of adding a P2Y12 …

Isothiocyanates (ITCs) are nonnutrient compounds in cruciferous vegetables with
anticarcinogenic properties. One proposed mechanism for their protective action is through down-…