Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised
and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (…

Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort
ever assembled. Methods Our sample was a multisite international SLE cohort (23 centers…

Background Since anecdotal series and small, prospective, controlled trials suggest that
mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are desirable. …

It has long been recognized that environmental influences play an important role in the risk
of developing chronic rheumatic disease. Defining specific pathogenic environmental …

Background Oral contraceptives are rarely prescribed for women with systemic lupus
erythematosus, because of concern about potential negative side effects. In this double-blind, …

Recent studies have suggested that mycophenolate mofetil (MMF) may offer advantages
over intravenous cyclophosphamide (IVC) for the treatment of lupus nephritis, but these …

Background: There is concern that exogenous female hormones may worsen disease activity
in women with systemic lupus erythematosus (SLE). Objective: To evaluate the effect of …

Background Maintenance therapy, often with azathioprine or mycophenolate mofetil, is
required to consolidate remission and prevent relapse after the initial control of lupus nephritis. …

Objective In systemic lupus erythematosus (SLE), disease activity and glucocorticoid (GC)
exposure are known to contribute to irreversible organ damage. We aimed to examine the …

Background and aims We studied damage accrual and factors determining development
and progression of damage in an international cohort of systemic lupus erythematosus (SLE) …