User profiles for L. Chiche

Laurence Chiche

Professor of Surgery
Verified email at chu-bordeaux.fr
Cited by 11186

Squash inhibitors: from structural motifs to macrocyclic knottins

L Chiche, A Heitz, JC Gelly, J Gracy… - Current Protein and …, 2004 - ingentaconnect.com
In this article, we will first introduce the squash inhibitors, a well established family of highly
potent canonical serine proteinase inhibitors isolated from Cucurbitaceae. The squash …

Digestive oncology: surgical practices

…, S Berdah, G Champault, L Chiche… - Journal de …, 2009 - pubmed.ncbi.nlm.nih.gov
[Digestive oncology: surgical practices] [Digestive oncology: surgical practices] J Chir (Paris).
2009 May;146 Suppl 2:S11-80. doi: 10.1016/S0021-7697(09)72398-1. [Article in French] …

Immune-checkpoint inhibitor use in patients with cancer and pre-existing autoimmune diseases

A Tison, S Garaud, L Chiche, D Cornec… - Nature Reviews …, 2022 - nature.com
Immune-checkpoint inhibitors (ICIs) have dramatically changed the management of advanced
cancers. Designed to enhance the antitumour immune response, they can also cause off-…

Adrenocortical carcinoma extending into the inferior vena cava: presentation of a 15-patient series and review of the literature

L Chiche, B Dousset, E Kieffer, Y Chapuis - Surgery, 2006 - Elsevier
BACKGROUND: Involvement of the inferior vena cava (IVC) is a controversial risk factor for
surgical treatment of adrenocortical carcinoma (ACC). This study aims to assess the outcome …

Implications cliniques de la découverte d'une hypervitaminémie B12 en médecine interne

L Chiche, R Jean, F Romain, F Roux, G Thomas… - La Revue de médecine …, 2008 - Elsevier
Propos La fréquence de la carence en vitamine B12 a, pour conséquence, une prescription
courante du dosage de la vitaminémie B12 dans un service de médecine interne, qui peut …

Clinical practice guidelines on the use of liver biopsy

…, M Bourlière, L Chiche… - Gastroenterologie …, 2002 - pubmed.ncbi.nlm.nih.gov
… 1 , Jean-François Cadranel, Georges Bonnemaison, Marc Bourlière, Laurence Chiche,
Hélène Chor, Marie-Hélène Denninger, Françoise Degos, Emmanuel Jacquemin, Brigitte …

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

C Luci, A Reynders, II Ivanov, C Cognet, L Chiche… - Nature …, 2009 - nature.com
NKp46 + CD3 − natural killer lymphocytes isolated from blood, lymphoid organs, lung, liver
and uterus can produce granule-dependent cytotoxicity and interferon-γ. Here we identify in …

Treatment of primary Sjögren syndrome with rituximab: a randomized trial

…, J Sibilia, JE Gottenberg, L Chiche… - Annals of internal …, 2014 - acpjournals.org
Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by
ocular and oral dryness or systemic manifestations. Objective: To evaluate efficacy and …

Squash Trypsin Inhibitors from Momordica cochinchinensis Exhibit an Atypical Macrocyclic Structure

JF Hernandez, J Gagnon, L Chiche, TM Nguyen… - Biochemistry, 2000 - ACS Publications
Three trypsin inhibitors (TIs), from the seeds of the squash Momordica cochinchinensis (MCo),
have been isolated and purified using gel filtration, ion exchange chromatography, and …

Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures

L Chiche, N Jourde‐Chiche, E Whalen… - Arthritis & …, 2014 - Wiley Online Library
Objective The role of interferon‐α (IFNα) in the pathogenesis of systemic lupus erythematosus
(SLE) is strongly supported by gene expression studies. The aim of this study was to …