Background Biologics are used for the treatment of rheumatoid arthritis and many other
conditions. While the efficacy of biologics has been established, there is uncertainty regarding …

Systematic reviews are difficult to keep up to date, but failure to do so leads to a decay in
review currency, accuracy, and utility. We are developing a novel approach to systematic …

The Visual Analogue Scale (VAS), Numeric Rating Scale (NRS), and Pain Severity subscale
of the Brief Pain Inventory (BPI-PS) are the most frequently used instruments to measure …

Background Osteoarthritis, a common joint disorder, is one of the leading causes of disability.
Chondroitin has emerged as a new treatment. Previous meta‐analyses have shown …

Background Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases. There
is currently no consensus on what is the best treatment to improve OA symptoms and slow …

Background TNF (tumor necrosis factor)‐alpha inhibitors block a key protein in the
inflammatory chain reaction responsible for joint inflammation, pain, and damage in ankylosing …

New approaches to evidence synthesis, which use human effort and machine automation in
mutually reinforcing ways, can enhance the feasibility and sustainability of living systematic …

Background Physical functioning is a core outcome domain to be measured in nonspecific
low back pain (NSLBP). A panel of experts recommended the Roland-Morris Disability …

While it is important for the evidence supporting practice guidelines to be current, that is
often not the case. The advent of living systematic reviews has made the concept of “living …

The Cochrane Musculoskeletal Group (CMSG), one of 53 groups of the not-for-profit, international
Cochrane Collaboration, prepares, maintains, and disseminates systematic reviews of …