Background The treatment of rheumatoid arthritis should aim at clinical remission. This
multicentre, randomised trial with 2-year follow-up sought evidence on the efficacy and tolerability …

Treating to target by monitoring disease activity and adjusting therapy to attain remission or
low disease activity has been shown to lead to improved outcomes in chronic rheumatic …

Objective To evaluate the long‐term frequency of disease remissions and the progression of
joint damage in patients with early rheumatoid arthritis (RA) who were initially randomized …

Objective To explore the impact of an early treatment response on maintenance of work
capacity in patients with early, active rheumatoid arthritis (RA). Methods In the Finnish …

Objective To compare the efficacy of therapy with a combination of disease‐modifying
antirheumatic drugs (DMARDs) versus therapy with a single DMARD in the prevention of work …

John Dewey is, with Charles Sanders Peirce and William James, one of the leading early
figures of the school of American Pragmatists. He has also had a great deal of influence in …

Introduction Early treatment of rheumatoid arthritis (RA) has been shown to retard the development
of joint damage for a period of up to 5 years. The aim of this study was to evaluate the …

Objective: To explore baseline risk factors for productivity loss and work disability over 5 years
in patients with early, active RA. Patients and methods: In the FIN-RACo trial, 195 patients …

Objective Early treatment of patients with rheumatoid arthritis (RA) with combination
treatment starting with methotrexate, sulfasalazine, hydroxychloroquine and prednisolone (FIN-…

Objective. Because of the role of tumor necrosis factor (TNF) in host defense, it was hypothesized
that its inhibition might lead to an increased risk of malignancies and infections. The …