Purpose Our aim was to perform a systematic review of the methods currently being used to
assess adherence and persistence in pharmacoepidemiological and pharmacoeconomic …

Composed of trillions of individual microbes, the human gut microbiota has adapted to the
uniquely diverse environments found in the human intestine. Quickly responding to the …

Zinc oxide has a variety of applications in catalysis both as support and as active phase for
hydrogenation or dehydrogenation reactions. This review provides an overview of the surface …

The cytoarchitecture of nervous tissue is lost during the dissociation procedures used to form
primary cell cultures. As a first step toward reestablishing an ordered arrangement of these …

Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response
to a variety of endoplasmic reticulum stresses implicated in numerous disease states. …

Background Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody,
has been approved for the treatment of metastatic melanoma and induces adverse events (AE) …

In alignment with the International Council of Harmonization’s strategic goals, a public-private
consortium has developed a structured template for planning and reporting on the …

We present a versatile construction and deformation method for head models with anatomical
structure, suitable for real-time physics-based facial animation. The model is equipped …

Aim Programmed cell death protein 1 (PD-1) inhibitors are a common treatment strategy for
metastatic melanoma and other tumour entities. Clinical trials usually exclude patients with …

… We build our system on the deformable, anatomy-based head model described by Kahler
et al. [2002]. There, a generic face mesh with underlying muscle and bone layers is deformed …