User profiles for J. D. CLARK

Jon D. Clark

Professor and Chair, Computer Information Systems
Verified email at colostate.edu
Cited by 5130

Opioid-induced hyperalgesia: a qualitative systematic review

MS Angst, JD Clark - The Journal of the American Society of …, 2006 - pubs.asahq.org
Clark JD: Chronic pain prevalence and analgesic prescribing in a general medical … Liang
D, Li X, Lighthall G, Clark JD: Heme oxygenase type 2 modulates behavioral and molecular …

Cytosolic phospholipase A2

JD Clark, AR Schievella, EA Nalefski, LL Lin - Journal of lipid mediators …, 1995 - Elsevier
Arachidonic acid is liberated from the sn-2 position of membrane glycerophospholipids by
phospholipase A,(PLA,), initiating the production of prostaglandins and leukotrienes, …

Discovery and development of Janus Kinase (JAK) inhibitors for inflammatory diseases: Miniperspective

JD Clark, ME Flanagan, JB Telliez - Journal of medicinal chemistry, 2014 - ACS Publications
The Janus kinases (JAKs) are a family of intracellular tyrosine kinases that play an essential
role in the signaling of numerous cytokines that have been implicated in the pathogenesis of …

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

JD Clark, LL Lin, RW Kriz, CS Ramesha, LA Sultzman… - Cell, 1991 - cell.com
We report the cloning and expression of a cDNA encoding a high molecular weight (85.2 kd)
cytosolic phospholipase Az (cPLA2) that has no detectable sequence homology with the …

Suppression of aging in mice by the hormone Klotho

H Kurosu, M Yamamoto, JD Clark, JV Pastor, A Nandi… - Science, 2005 - science.org
A defect in Klotho gene expression in mice accelerates the degeneration of multiple age-sensitive
traits. Here, we show that overexpression of Klotho in mice extends life span. Klotho …

The immune epitope database (IEDB) 3.0

…, JA Greenbaum, J Ponomarenko, JD Clark… - Nucleic acids …, 2015 - academic.oup.com
The IEDB, www.iedb.org , contains information on immune epitopes—the molecular targets
of adaptive immune responses—curated from the published literature and submitted by …

[HTML][HTML] Regulation of Oxidative Stress by the Anti-aging Hormone Klotho*♦

M Yamamoto, JD Clark, JV Pastor, P Gurnani… - Journal of Biological …, 2005 - ASBMB
klotho is an aging suppressor gene and extends life span when overexpressed in mice.
Klotho protein was recently demonstrated to function as a hormone that inhibits insulin/insulin-…

Environment and behavior of 2.5-million-year-old Bouri hominids

J Heinzelin, JD Clark, T White, W Hart, P Renne… - Science, 1999 - science.org
The Hata Member of the Bouri Formation is defined for Pliocene sedimentary outcrops in the
Middle Awash Valley, Ethiopia. The Hata Member is dated to 2.5 million years ago and has …

The 1996 guide for the care and use of laboratory animals

JD Clark, GF Gebhart, JC Gonder, ME Keeling… - ILAR …, 1997 - academic.oup.com
Laboratory Animal Facilities and Care and was revised in 1965, 1968, 1972, 1978, and
1985. More than 400,000 copies have been distributed since it was first published, and it is …

[PDF][PDF] The prehistory of southern Africa

JD Clark - Harmondsworth, England, 1959 - repository.out.ac.tz
… Pleistocene main faunal and fossil man localities in southern Africa (after JD Clark,ˇ gjd) …
20.5 Wooden implements from Pleistocene sites m southern Africa (after JD Clark, 1970): 1, The …