Analyzing time series gene expression data

Z Bar-Joseph - Bioinformatics, 2004 - academic.oup.com
… can be used when the class information is not given (Bar-Joseph et al., 2003c). This results
in … the leaves of an hierarchical clustering tree was presented in Bar-Joseph et al. (2003a). By …

The continuous challenge of citrus tristeza virus control

M Bar-Joseph, R Marcus, RF Lee - Annual review of …, 1989 - annualreviews.org
Bar-Joseph et al (17) reported a quantitative difference in the number of particles when
comparing seedling yellows and ordinary CTV strains in Israel. Sasaki et aI (155) separated mild …

Studying and modelling dynamic biological processes using time-series gene expression data

Z Bar-Joseph, A Gitter, I Simon - Nature Reviews Genetics, 2012 - nature.com
Biological processes are often dynamic, thus researchers must monitor their activity at multiple
time points. The most abundant source of information regarding such dynamic activity is …

Computational discovery of gene modules and regulatory networks

Z Bar-Joseph, GK Gerber, TI Lee, NJ Rinaldi… - Nature …, 2003 - nature.com
We describe an algorithm for discovering regulatory networks of gene modules, GRAM (Genetic
Regulatory Modules), that combines information from genome-wide location and …

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

TI Lee, NJ Rinaldi, F Robert, DT Odom, Z Bar-Joseph… - science, 2002 - science.org
We have determined how most of the transcriptional regulators encoded in the eukaryote
Saccharomyces cerevisiaeassociate with genes across the genome in living cells. Just as …

[HTML][HTML] STEM: a tool for the analysis of short time series gene expression data

J Ernst, Z Bar-Joseph - BMC bioinformatics, 2006 - Springer
Background Time series microarray experiments are widely used to study dynamical biological
processes. Due to the cost of microarray experiments, and also in some cases the limited …

The sirtuin SIRT6 regulates lifespan in male mice

…, G Amir, V Peshti, G Zinman, L Nahum, Z Bar-Joseph… - Nature, 2012 - nature.com
The significant increase in human lifespan during the past century confronts us with great
medical challenges. To meet these challenges, the mechanisms that determine healthy ageing …

Matter-wave interferometry in a double well on an atom chip

…, LM Andersson, S Wildermuth, S Groth, I Bar-Joseph… - Nature physics, 2005 - nature.com
Matter-wave interference experiments enable us to study matter at its most basic, quantum
level and form the basis of high-precision sensors for applications such as inertial and …

Fast optimal leaf ordering for hierarchical clustering

Z Bar-Joseph, DK Gifford, TS Jaakkola - Bioinformatics, 2001 - academic.oup.com
We present the first practical algorithm for the optimal linear leaf ordering of trees that are
generated by hierarchical clustering. Hierarchical clustering has been extensively used to …

[HTML][HTML] The formation of highly soluble oligomers of α-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

R Sharon, I Bar-Joseph, MP Frosch, DM Walsh… - Neuron, 2003 - cell.com
Accumulation of misfolded proteins as insoluble aggregates occurs in several neurodegenerative
diseases. In Parkinson's disease (PD) and dementia with Lewy bodies (DLB), α-…