User profiles for G. SCHETT

Georg Andreas Schett

FAU Erlangen-Nürnberg
Verified email at uk-erlangen.de
Cited by 98619

The pathogenesis of rheumatoid arthritis

IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The increased understanding of the immune mechanisms of rheumatoid arthritis has led to
the development of a considerable number of new therapeutic agents that alter the natural …

Cytokines in the pathogenesis of rheumatoid arthritis

IB McInnes, G Schett - Nature Reviews Immunology, 2007 - nature.com
Cytokines regulate a broad range of inflammatory processes that are implicated in the
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …

Pathogenetic insights from the treatment of rheumatoid arthritis

IB McInnes, G Schett - The Lancet, 2017 - thelancet.com
Rheumatoid arthritis is a chronic autoimmune disease that causes progressive articular
damage, functional loss, and comorbidity. The development of effective biologics and small-…

Dickkopf-1 is a master regulator of joint remodeling

…, R Landewe, D Lacey, WG Richards, G Schett - Nature medicine, 2007 - nature.com
Degenerative and inflammatory joint diseases lead to a destruction of the joint architecture.
Whereas degenerative osteoarthritis results in the formation of new bone, rheumatoid …

[HTML][HTML] European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update

…, IB McInnes, I Olivieri, K Pavelka, G Schett… - Annals of the …, 2016 - ard.bmj.com
Background Since the publication of the European League Against Rheumatism recommendations
for the pharmacological treatment of psoriatic arthritis (PsA) in 2012, new evidence …

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus

…, KM Habenicht, TH Winkler, G Krönke, G Schett - Nature medicine, 2022 - nature.com
… Furthermore, residual proteinuria (0.3 g/g creatinine) successively improved with dose
adaptation of angiotensin-converting enzyme (ACE) inhibitors after 3 months. Nephritis ceased in …

EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update

…, D Poddubnyy, SAR Manica, G Schett… - Annals of the …, 2020 - ard.bmj.com
Objective To update the European League Against Rheumatism (EULAR) recommendations
for the pharmacological treatment of psoriatic arthritis (PsA). Methods According to the …

[HTML][HTML] Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

…, L Klareskog, P Jurdic, G Schett - The Journal of …, 2012 - Am Soc Clin Investig
… To separate digested protein from the Immobilized Pepsin, the solution was centrifuged at
1,000 g for 5 minutes. The supernatant-containing digested protein was decanted into a new …

[HTML][HTML] Osteoclasts are essential for TNF-α–mediated joint destruction

…, JS Smolen, EF Wagner, G Schett - The Journal of …, 2002 - Am Soc Clin Investig
… Cooperative Project (ICP) of the Austrian Federal Ministry for Education, Science and Culture
and the City of Vienna, and a grant from the Austrian National Bank (project 8715, G. Schett

[HTML][HTML] Trial of tocilizumab in giant-cell arteritis

…, J Rech, C Salvarani, G Schett… - … England Journal of …, 2017 - Mass Medical Soc
Background Giant-cell arteritis commonly relapses when glucocorticoids are tapered, and the
prolonged use of glucocorticoids is associated with side effects. The effect of the interleukin…