User profiles for E. C. Goligher

Ewan Goligher

University of Toronto
Verified email at mail.utoronto.ca
Cited by 13429

[HTML][HTML] Esophageal and transpulmonary pressure in the clinical setting: meaning, usefulness and perspectives

T Mauri, T Yoshida, G Bellani, EC Goligher… - Intensive care …, 2016 - Springer
Purpose Esophageal pressure (Pes) is a minimally invasive advanced respiratory monitoring
method with the potential to guide management of ventilation support and enhance …

[HTML][HTML] Critical illness-associated diaphragm weakness

M Dres, EC Goligher, LMA Heunks, LJ Brochard - Intensive Care Medicine, 2017 - Springer
Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU
admission and may precipitate the need for mechanical ventilation but it also frequently develops …

[HTML][HTML] Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort

EC Goligher, AH Jonkman, J Dianti, K Vaporidi… - Intensive care …, 2020 - Springer
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

An official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation …

E Fan, L Del Sorbo, EC Goligher… - American journal of …, 2017 - atsjournals.org
Background: This document provides evidence-based clinical practice guidelines on the use
of mechanical ventilation in adult patients with acute respiratory distress syndrome (ARDS). …

Mechanical ventilation–induced diaphragm atrophy strongly impacts clinical outcomes

EC Goligher, M Dres, E Fan, GD Rubenfeld… - American journal of …, 2018 - atsjournals.org
Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and function …

Evolution of diaphragm thickness during mechanical ventilation. Impact of inspiratory effort

EC Goligher, E Fan, MS Herridge, A Murray… - American journal of …, 2015 - atsjournals.org
Rationale: Diaphragm atrophy and dysfunction have been reported in humans during
mechanical ventilation, but the prevalence, causes, and functional impact of changes in …

Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and posterior probability of mortality benefit in a post hoc Bayesian analysis of a …

EC Goligher, G Tomlinson, D Hajage… - Jama, 2018 - jamanetwork.com
Goligher had full access to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis. Drs Tomlinson and Goligher … : Dr Goligher

[HTML][HTML] Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity

EC Goligher, F Laghi, ME Detsky, P Farias… - Intensive care …, 2015 - Springer
Purpose Ultrasound measurements of diaphragm thickness (T di ) and thickening (TF di )
may be useful to monitor diaphragm activity and detect diaphragm atrophy in mechanically …

[HTML][HTML] The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

…, J Mancebo, T Mauri, Y Helviz, EC Goligher… - Intensive care …, 2020 - Springer
Purpose High flow nasal cannula (HFNC) is a relatively recent respiratory support technique
which delivers high flow, heated and humidified controlled concentration of oxygen via the …

Lung-and diaphragm-protective ventilation

EC Goligher, M Dres, BK Patel, SK Sahetya… - American journal of …, 2020 - atsjournals.org
Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is
associated with poor clinical outcomes. Although the importance and impact of lung-protective …