The Study Group for Risk Factors for Rheumatoid Arthritis was established by the EULAR
Standing Committee on Investigative Rheumatology to facilitate research into the preclinical …

… However, 25-hydroxy vitamin D (25(OH)D) levels, which reflect vitamin D absorption by UV
light exposure, inversely correlate with MS risk in white individuals (86, 87). 25(OH)D levels …

… the Jan van Breemen Institute, a regional network of outpatient clinics. In 1999, a letter was
sent to all 5,000 registered patients with RA in the diagnosis registry of the Jan van Breemen …

… “arthritis” and “rheumatoid arthritis,” and d) a search strategy for the identification of studies
… The best evidence synthesis (Table 1) was based upon the one proposed by Van Tulder et …

Background: Rheumatoid arthritis is characterised by inflammation and an increased
cardiovascular risk. It was recently shown that active early rheumatoid arthritis is associated with …

Objective There are insufficient data on the effects of long‐term intensive exercise in patients
with rheumatoid arthritis (RA). We undertook this randomized, controlled, multicenter trial to …

Background The aetiology of rheumatoid arthritis (RA), a prototype immune-mediated
inflammatory disorder, is poorly understood. It is currently unknown whether the disease process …

… Carola JE Kaandorp, MD, Dirkjan van Schaardenburg, MD: Jan van Breemen Institute for
Rheumatology and Rehabilitation, Amsterdam, The Netherlands; Pieta Krijnen, MS, J. Dik F. …

Background Anti-citrullinated protein antibodies (ACPA) are associated with increased risk
for rheumatoid arthritis. Objective To investigate the effect of the presence and levels of ACPA …

Background During the transition to rheumatoid arthritis (RA) many patients pass through a
phase characterised by the presence of symptoms without clinically apparent synovitis. …