User profiles for D. D'Cruz

David D'Cruz

King's College London and Guy's Hospital
Verified email at kcl.ac.uk
Cited by 24110

Immunosuppressive therapy in lupus nephritis: the Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide

FA Houssiau, C Vasconcelos, D D'Cruz… - Arthritis & …, 2002 - Wiley Online Library
Objective Glomerulonephritis is a severe manifestation of systemic lupus erythematosus (SLE)
that is usually treated with an extended course of intravenous (IV) cyclophosphamide (…

[PDF][PDF] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

…, SK Biswas, D Moshous, C Picard, JP Jais, D D'Cruz… - Immunity, 2010 - cell.com
Monocytes are effectors of the inflammatory response to microbes. Human CD14 +
monocytes specialize in phagocytosis and production of reactive oxygen species and secrete …

BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic …

…, E Allen, V Farewell, M Akil, IN Bruce, D D'cruz… - …, 2005 - academic.oup.com
Objective. To devise a more discriminating version of the British Isles Lupus Assessment
Group (BILAG) disease activity index and to show that it is reliable. Methods. A nominal …

The 10-year follow-up data of the Euro-Lupus Nephritis Trial comparing low-dose and high-dose intravenous cyclophosphamide

FA Houssiau, C Vasconcelos, D D'Cruz… - Annals of the …, 2010 - ard.bmj.com
Objective: To update the follow-up of the Euro-Lupus Nephritis Trial (ELNT), a randomised
prospective trial comparing low-dose (LD) and high-dose (HD) intravenous (IV) …

Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial

FA Houssiau, D D'Cruz, S Sangle, P Remy… - Annals of the …, 2010 - ard.bmj.com
Background Long-term immunosuppressive treatment does not efficiently prevent relapses
of lupus nephritis (LN). This investigator-initiated randomised trial tested whether …

The efficacy and safety of abatacept in patients with non–life‐threatening manifestations of systemic lupus erythematosus: results of a twelve‐month, multicenter …

…, R Westhovens, A Chalmers, D D'cruz… - Arthritis & …, 2010 - Wiley Online Library
D'Cruz has received consulting fees from Bristol-Myers Squibb and has served as a … D'Cruz
has received consulting fees from Bristol-Myers Squibb and has served as a member of their …

Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long‐term followup of patients in the Euro‐Lupus Nephritis …

FA Houssiau, C Vasconcelos, D D'Cruz… - Arthritis & …, 2004 - Wiley Online Library
Objective In the Euro‐Lupus Nephritis Trial (ELNT), 90 patients with lupus nephritis were
randomly assigned to a high‐dose intravenous cyclophosphamide (IV CYC) regimen (6 …

[HTML][HTML] The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome

…, G Zandman-Goddard, EG Meyron-Holtz, DP D'Cruz… - BMC medicine, 2013 - Springer
Background Over the last few years, accumulating data have implicated a role for ferritin as
a signaling molecule and direct mediator of the immune system. Hyperferritinemia is …

BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis

…, D Carruthers, K Chakravarty, D D'Cruz… - …, 2014 - academic.oup.com
… People with a suspected diagnosis of systemic vasculitis should be rapidly assessed by a
specialist physician with an expertise in vasculitis (D). Self-referral mechanisms should be in …

The human horizontal vestibulo-ocular reflex in response to high-acceleration stimulation before and after unilateral vestibular neurectomy

…, MJ Todd, MJ Staples, DM D'cruz - Experimental brain …, 1990 - Springer
The normal horizontal vestibulo-ocular reflex (HVOR) is largely generated by simultaneous
stimulation of the two horizontal semicircular canals (HSCCs). To determine the dynamics of …