Within the past decade, musculoskeletal ultrasound (US) has become an established imaging
technique for the diagnosis and follow up of patients with rheumatic diseases. 1–5 This …

The role of the T3/antigen receptor complex is summarized by the diagram presented in
Figure 4. Signals transmitted through T3/Ti activate a phosphodiesterase. This enzyme acts on …

… alphaviruses (such as Chikungunya, Ross River, Barmah Forest, Sindbis, O’nyong-nyong
and Mayaro viruses), self-limited arthritis occurs with parvovirus B19, rubella or hepatitis B …

Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting
bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct …

… Manger has received honoraria of less than $10,000 from Essex, Wyeth, Abbott, and Novartis.
Dr. Weisman has received consulting fees of less than $10,000 from Bristol-Myers Squibb, …

… (b) Representative tissue sections from an individual with gout, including a tophus, and
from a subject with non-gouty synovitis stained with PI and an antibody to NE. White arrows …

… for autoreactive B cells. This action may override an important control mechanism for B
cell … In the case of anti-dsDNA, histones may provide T cell epitopes, whereas B cell–specific …

… B cells play a key role in the pathogenesis of SLE, B-cell … and persistence of autoreactive B
cells within lymphatic organs and … to recognize CD19 and other B-cell surface antigens have …

Objective Anticitrullinated protein antibodies (ACPA) are a major risk factor for bone loss in
rheumatoid arthritis (RA). We have recently shown that ACPA directly induce bone loss by …

… Our main objectives were (A) to estimate the association between persistent highly active
disease and mortality and (B) to evaluate the mortality risk of patients treated with TNFα …