Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?
AN Malik, A Czajka - Mitochondrion, 2013 - Elsevier
Mitochondrial dysfunction is central to numerous diseases of oxidative stress. Changes in
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …
Hot weather and heat extremes: health risks
…, G Havenith, Y Honda, RS Kovats, W Ma, A Malik… - The lancet, 2021 - thelancet.com
Hot ambient conditions and associated heat stress can increase mortality and morbidity, as
well as increase adverse pregnancy outcomes and negatively affect mental health. High heat …
well as increase adverse pregnancy outcomes and negatively affect mental health. High heat …
Signaling mechanisms regulating endothelial permeability
D Mehta, AB Malik - Physiological reviews, 2006 - journals.physiology.org
The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …
Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation
CG Williams, AN Malik, TK Kim, PN Manson… - Biomaterials, 2005 - Elsevier
The development of biocompatible photopolymerizing polymers for biomedical and tissue
engineering applications has the potential to reduce the invasiveness and cost of biomaterial …
engineering applications has the potential to reduce the invasiveness and cost of biomaterial …
Activity-dependent regulation of inhibitory synapse development by Npas4
Neuronal activity regulates the development and maturation of excitatory and inhibitory
synapses in the mammalian brain. Several recent studies have identified signalling networks …
synapses in the mammalian brain. Several recent studies have identified signalling networks …
[PDF][PDF] Using whole-exome sequencing to identify inherited causes of autism
Despite significant heritability of autism spectrum disorders (ASDs), their extreme genetic
heterogeneity has proven challenging for gene discovery. Studies of primarily simplex families …
heterogeneity has proven challenging for gene discovery. Studies of primarily simplex families …
Genome-wide identification and characterization of functional neuronal activity–dependent enhancers
Experience-dependent gene transcription is required for nervous system development and
function. However, the DNA regulatory elements that control this program of gene expression …
function. However, the DNA regulatory elements that control this program of gene expression …
[HTML][HTML] COVID-19 vaccine acceptance and hesitancy in low-and middle-income countries
Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization
coverage to end the global pandemic, yet few studies have investigated COVID-19 …
coverage to end the global pandemic, yet few studies have investigated COVID-19 …
On the opportunities and risks of foundation models
AI is undergoing a paradigm shift with the rise of models (eg, BERT, DALL-E, GPT-3) that are
trained on broad data at scale and are adaptable to a wide range of downstream tasks. We …
trained on broad data at scale and are adaptable to a wide range of downstream tasks. We …
[HTML][HTML] Determinants of COVID-19 vaccine acceptance in the US
Background The COVID-19 pandemic continues to adversely affect the US, which leads
globally in total cases and deaths. As COVID-19 vaccines are under development, public health …
globally in total cases and deaths. As COVID-19 vaccines are under development, public health …