Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Acute massive pulmonary embolism has a high mortality rate. Fatal haemodynamic
deterioration is caused by an acute increase in pulmonary vascular resistance. Traditionally, the …

Please cite this paper as: de Boer, Meijer, Wijnstok, Jonk, Houben, Stehouwer, Smulders,
Eringa and Serné (2012). Microvascular Dysfunction: A Potential Mechanism in the …

Microalbuminuria is a strong and independent indicator of increased cardiovascular risk
among individuals with and without diabetes. Therefore, microalbuminuria can be used for …

Objective Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular
disease (CVD), but longitudinal observations are limited and the precise magnitude is …

There is increasing evidence that scientific misconduct is more common than previously
thought. Strong emphasis on scientific productivity may increase the sense of publication …

Endothelial dysfunction and low-grade inflammation are associated with cardiovascular
disease. Arterial stiffening plays an important role in cardiovascular disease and, thus, may be a …

OBJECTIVES:: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular
disease. Carotid intima media thickness (cIMT) is frequently used to identify populations at …

Mild to moderate hyperhomocysteinemia has been identified as a strong predictor of cardiovascular
disease, independent from classical atherothrombotic risk factors. In the last decade, …

434 Hypertension March 2014 to damage sensitive target organs, as well as impair vascular
function, and thereby to contribute to a vicious cycle of arterial remodeling. Blood flow …