Polymorphisms of IL-1 beta gene in Japanese patients with Sjögren's syndrome and systemic lupus erythematosus.

…, R Takahashi, E Suzuki, T Hayashi, Y Chino… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: Interleukin (IL)-1 beta is a proinflammatory cytokine involved in various
immune responses. Five polymorphisms in the IL-1 beta gene have been described, and …

Significance of antiprothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the …

A Tsutsumi, T Hayashi, Y Chino, M Mamura… - Modern …, 2006 - Taylor & Francis
Antibodies against prothrombin are detected by enzyme immunoassays (EIA) in sera of
patients with antiphospholipid syndrome (APS). However, there are two methods for …

Early diagnosis and treatment of steroid-induced diabetes mellitus in patients with rheumatoid arthritis and other connective tissue diseases

…, Y Kondo, M Sugihara, T Hayashi, Y Chino… - Modern …, 2014 - Taylor & Francis
Purpose To reveal how often patients with rheumatoid arthritis (RA) or any of other connective
tissue diseases (CTDs) who take prednisolone (PSL) manifest postprandial hyperglycemia…

Clinical features of patients with IgG4-related disease complicated with perivascular lesions

…, Y Kondo, H Ogishima, T Suzuki, Y Chino… - Modern …, 2015 - academic.oup.com
Objective. To define the clinical features of IgG4-related disease (IgG4-RD) complicated
with perivascular lesions. Methods. The clinical features of seven patients with IgG4-RD and …

Effects of infliximab therapy on gene expression levels of tumor necrosis factor α, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with …

…, H Ogishima, T Hayashi, Y Chino… - … : Official Journal of …, 2007 - Wiley Online Library
Objective Tristetraprolin (TTP), T cell intracellular antigen 1 (TIA‐1), and Hu antigen R (HuR)
are adenine/uridine‐rich element binding proteins (ABPs) that affect the production of tumor …

Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals

…, M Sugihara, Y Muraki, T Hayashi, Y Chino… - Modern …, 2008 - academic.oup.com
Tristetraprolin (TTP) is an intracellular protein that modulates the production of cytokines,
including TNFα, by binding to and destabilizing the mRNAs of these cytokines. Therefore, …

Use of laser microdissection in the analysis of renal-infiltrating T cells in MRL/lpr mice

Y Wang, S Ito, Y Chino, K Iwanami… - Modern …, 2008 - academic.oup.com
To clarify the role of T cells in the kidneys of MRL/MpJ-lpr (MRL/lpr) mice, cytokine mRNA
expression was analyzed, and tissue localization of T cells was examined by …

Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production

Y Muraki, I Matsumoto, Y Chino, T Hayashi… - Biochemical and …, 2004 - Elsevier
Glucose-6-phosphate isomerase (GPI), recognized as an autoantigen in the K/BxN arthritis
model, is a ubiquitous cytoplasmic enzyme. Anti-GPI antibodies (Abs) are also detected in …

Therapeutic efficacy of tocilizumab in patients with rheumatoid arthritis refractory to anti-tumor-necrosis-factor inhibitors: 1 year follow-up with low-field extremity MRI

…, Y Kondo, H Tsuboi, T Hayashi, Y Chino… - Modern …, 2013 - Taylor & Francis
Objective Tocilizumab (TCZ) is effective in patients with rheumatoid arthritis (RA) who are
refractory to anti-tumor-necrosis-factor (anti-TNF) biologics. The Rheumatoid Arthritis Society …

Reiter's syndrome following intravesical bacille bilié de Calmette–Guérin treatment for superficial bladder carcinoma: report of six cases

H Murata, Y Adachi, T Ebitsuka, Y Chino… - Modern …, 2004 - academic.oup.com
We report the cases of six patients who developed acute Reiter’s syndrome following intravesical
bacille bilié de Calmette–Guérin (BCG) immunotherapy for superficial bladder cancer. …