A nuclear antigen associated with cell proliferation and blast transformation.

Y Takasaki, JS Deng, EM Tan - The Journal of experimental medicine, 1981 - rupress.org
A nuclear antigen associated with cell proliferation (proliferating cell nuclear antigen-PCNA)
and blast transformation is recognized by autoantibodies in the sera of some patients with …

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

…, FL Liu, DM Chang, Y Takasaki… - Proceedings of the …, 2010 - National Acad Sciences
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disease that predominantly
affects women. Previous findings that duplicated Toll-like receptor 7 (Tlr7) promotes lupus…

Anti‐DFS70 antibodies in 597 healthy hospital workers

…, K Sugiura, T Usuda, EM Tan, Y Takasaki… - Arthritis & …, 2004 - Wiley Online Library
Objective Autoantibodies against DFS70 (dense fine speckles 70) antigen (also known as
lens epithelium–derived growth factor) have been recently identified among the antinuclear …

[HTML][HTML] Classification and characteristics of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception …

…, M Harigai, T Fujii, H Dobashi, Y Takasaki… - Arthritis research & …, 2014 - Springer
Introduction We investigated the clinical and serological features of patients with antineutrophil
cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in Japan using data from a …

A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities: I. Precision, sensitivity, and specificity

…, NF Rothfield, R Smeenk, Y Takasaki… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To determine the performance characteristics of enzyme‐based immunoassay (EIA)
kits for the detection of antinuclear and other autoantibodies of defined specificities. …

[HTML][HTML] A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese

…, Y Tanaka, T Sumida, H Yamanaka, Y Takasaki… - PLoS …, 2012 - journals.plos.org
Systemic lupus erythematosus (SLE) is an autoimmune disease that causes multiple organ
damage. Although recent genome-wide association studies (GWAS) have contributed to …

[HTML][HTML] The multicenter study of a new assay for simultaneous detection of multiple anti-aminoacyl-tRNA synthetases in myositis and interstitial pneumonia

…, K Fujio, K Yamamoto, H Kohsaka, Y Takasaki… - PloS one, 2014 - journals.plos.org
Objective Autoantibodies to aminoacyl-tRNA synthetases (ARSs) are useful in the diagnosis
of idiopathic inflammatory myopathy (IIM) with interstitial pneumonia (IP). We developed an …

[PDF][PDF] Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study

…, R Hara, Y Maejima, H Tsukamoto, Y Takasaki… - …, 2020 - academic.oup.com
Concise report Page 1 Concise report Long-term efficacy and safety of tocilizumab in
refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study …

Tofacitinib in combination with methotrexate in patients with rheumatoid arthritis: clinical efficacy, radiographic, and safety outcomes from a twenty‐four–month, phase …

…, SC Shim, V Shobha, Y Takasaki… - Arthritis & …, 2019 - Wiley Online Library
Objective Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis ( RA ).
The phase III , 24‐month, placebo‐controlled Oral Rheumatoid Arthritis ( ORAL ) Scan trial …

[HTML][HTML] Activation status of mucosal-associated invariant T cells reflects disease activity and pathology of systemic lupus erythematosus

…, M Kitagaichi, K Yamaji, Y Takasaki… - Arthritis research & …, 2017 - Springer
Background Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes constituting
a large proportion of peripheral blood T cells expressing αβ T-cell receptor in humans. …