Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis

Y Yoshihara, H Nakamura, K Obata… - Annals of the …, 2000 - ard.bmj.com
OBJECTIVE Matrix metalloproteinases (MMPs) are expressed in joint tissues of patients with
rheumatoid arthritis (RA) and osteoarthritis (OA). The objective of this study was to define …

[HTML][HTML] Cementless total hip replacement: past, present, and future

H Yamada, Y Yoshihara, O Henmi, M Morita… - Journal of Orthopaedic …, 2009 - Springer
Cementless total hip replacement (THR) is rapidly being accepted as the surgery for arthritic
diseases of the hip joint. The bone-ingrowth rate in porous-type cementless implants was …

Tissue engineering of articular cartilage with autologous cultured adipose tissue‐derived stromal cells using atelocollagen honeycomb‐shaped scaffold with a …

…, T Asazuma, H Hattori, Y Yoshihara… - … Research Part B …, 2006 - Wiley Online Library
Adipose tissue derived stromal cells (ATSCs), which were isolated from adipose tissue of
rabbit, have shown to possess multipotential, that is, they differentiate into osteoblasts and …

Increased levels of stromelysin‐1 and tissue inhibitor of metalloproteinases–1 in sera from patients with rheumatoid arthritis

Y Yoshihara, K Obata, N Fujimot… - … : Official Journal of …, 1995 - Wiley Online Library
Objective. To evaluate the efficacy of stromelysin‐1 (matrix metalloproteinase–3 [MMP‐3])
and tissue inhibitor of metalloproteinases–1 (TIMP‐1) in serum as markers for joint …

[HTML][HTML] Photodynamic Therapy Can Induce a Protective Innate Immune Response against Murine Bacterial Arthritis via Neutrophil Accumulation

…, L Huang, Y Morimoto, M Kinoshita, Y Yoshihara… - PloS one, 2012 - journals.plos.org
Background Local microbial infections induced by multiple-drug-resistant bacteria in the
orthopedic field can be intractable, therefore development of new therapeutic modalities is …

Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils

M Tanaka, M Kinoshita, Y Yoshihara… - Photochemistry and …, 2012 - Wiley Online Library
Photodynamic therapy (PDT) for localized microbial infections exerts its therapeutic effect both
by direct bacterial killing and also by the bactericidal effects of host neutrophils stimulated …

Enhancement of SPARC (osteonectin) synthesis in arthritic cartilage: increased levels in synovial fluids from patients with rheumatoid arthritis and regulation by growth …

…, M Noshiro, K Takahashi, Y Yoshihara… - … : Official Journal of …, 1996 - Wiley Online Library
Objective. To investigate the roles of SPARC (secreted protein, acidic and rich in cysteine) (osteonectin)
in arthritis, using cartilage and synovium specimens and synovial fluids (SF) …

Comparison of pedicle screw fixation strength among different transpedicular trajectories: a finite element study

…, H Imabayashi, N Hosogane, Y Yoshihara… - Clinical spine …, 2017 - journals.lww.com
Study Design: Comparative biomechanical study by finite element (FE) method. Objective:
To investigate the pullout strength of pedicle screws using different insertional trajectories. …

[PDF][PDF] Safety and immunogenicity of the Pfizer/BioNTech SARS-CoV-2 mRNA third booster vaccine dose against the BA. 1 and BA. 2 Omicron variants

Y Seki, Y Yoshihara, K Nojima, H Momose, S Fukushi… - Med, 2022 - cell.com
Background The Omicron variant of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)
was identified in Japan in November 2021. This variant contains up to 36 …

Joint fluid carboxy-terminal type II procollagen peptide as a marker of cartilage collagen biosynthesis

M Shinmei, K Ito, S Matsuyama, Y Yoshihara… - Osteoarthritis and …, 1993 - Elsevier
Joint fluid levels of carboxy-terminal type II procollagen peptide (pCOL II-C) were measured
in osteoarthritis, rheumatoid arthritis and traumatic arthritis by a newly developed one-step …