Clinical characteristics of patients with rheumatoid arthritis and methotrexate induced pneumonitis.
Y Ohosone, Y Okano, H Kameda, T Fujii… - The Journal of …, 1997 - europepmc.org
Objective To determine the clinical features of methotrexate (MTX) pneumonitis in patients
treated for rheumatoid arthritis (RA). Methods The medical records of 284 patients with RA …
treated for rheumatoid arthritis (RA). Methods The medical records of 284 patients with RA …
Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with …
T Mimori, Y Ohosone, N Hama… - Proceedings of the …, 1990 - National Acad Sciences
Anti-Ku (p70/p80) autoantibodies in patients with scleroderma-polymyositis overlap syndrome
recognize a 70-kDa/80-kDa protein heterodimer which binds to terminal regions of double-…
recognize a 70-kDa/80-kDa protein heterodimer which binds to terminal regions of double-…
Association of human leukocyte antigen class II genes with autoantibody profiles, but not with disease susceptibility in Japanese patients with systemic sclerosis
…, T Ogasawara, M Hirakata, Y Ohosone… - Internal …, 1999 - jstage.jst.go.jp
Methods: HLA-DRB1, DRB3, DRB4, DQB1, and DPB1 alleles were determined by genotyping;
and serum antinuclear antibodies were identified using indirect immunofluorescence, …
and serum antinuclear antibodies were identified using indirect immunofluorescence, …
Liver disease in systemic lupus erythematosus
A Suzuki, N Sekiyama, N Koito, Y Ohosone… - Japanese journal of …, 1995 - jstage.jst.go.jp
全身性エリテマトーデス (SLE) 193 例 (男性 17 例, 女性 176 例) を対象に SLE の肝障害について
検討した. 肝障害は各患者の初診時からの全経過を調べ Transaminase が 40IU/ml 以上を認めた…
検討した. 肝障害は各患者の初診時からの全経過を調べ Transaminase が 40IU/ml 以上を認めた…
Effect of intermittent cyclical etidronate therapy on corticosteroid induced osteoporosis in Japanese patients with connective tissue disease: 3 year followup.
S Sato, Y Ohosone, A Suwa, H Yasuoka… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: A 3 year prospective randomized study was conducted to clarify the efficacy of
intermittent cyclical etidronate therapy on corticosteroid induced osteoporosis. METHODS: A …
intermittent cyclical etidronate therapy on corticosteroid induced osteoporosis. METHODS: A …
A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B′
C Schmauss, G McAllister, Y Ohosone… - Nucleic acids …, 1989 - academic.oup.com
N is a tissue-specific, Sm-epitope bearing, snRNP-associated protein found predominantly in
brain. The cDNA sequence encoding human N is compared to those for rat N and human B/…
brain. The cDNA sequence encoding human N is compared to those for rat N and human B/…
Spectrum and clinical significance of autoantibodies against transfer RNA
Y Ohosone, M Ishida, Y Takahashi… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To characterize the clinical features of patients who have autoantibodies against
transfer RNA (tRNA) or tRNA-associated proteins. Methods Sera from 1,472 patients with …
transfer RNA (tRNA) or tRNA-associated proteins. Methods Sera from 1,472 patients with …
Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.
Y Ohosone, T Mimori, A Griffith… - Proceedings of the …, 1989 - National Acad Sciences
The Sm snRNPs play a central role in the processing of pre-mRNA. Anti-Sm antibodies, the
diagnostic hallmark of systemic lupus erythematosus, target the B'/B and D polypeptides of …
diagnostic hallmark of systemic lupus erythematosus, target the B'/B and D polypeptides of …
Mixed-cryoglobulinemia associated with cutaneous vasculitis and pulmonary symptoms
M Konishi, Y Ohosone, M MATSUMURA… - Internal …, 1997 - jstage.jst.go.jp
A45-year-old Japanese manwith Sjogren's syndromedeveloped recurrent skin ulcers, palpable
purpura, and dyspnea. Serummixed-type cryoglobulin level waselevated. Abiopsy of his …
purpura, and dyspnea. Serummixed-type cryoglobulin level waselevated. Abiopsy of his …
Autoantigenic epitopes of the B polypeptide of Sm small nuclear RNP particles
Y Ohosone, T Mimori, T Fujii, M Akizuki… - … : Official Journal of …, 1992 - Wiley Online Library
Objective. To analyze the autoantigenic epitopes of the Sm B polypeptide of the U1 small
nuclear RNP (snRNP) using complementary DNA (cDNA) clones. Methods. Expression of Sm …
nuclear RNP (snRNP) using complementary DNA (cDNA) clones. Methods. Expression of Sm …