Genetics of rheumatoid arthritis: 2018 status
Y Okada, S Eyre, A Suzuki, Y Kochi… - Annals of the rheumatic …, 2019 - ard.bmj.com
Study of the genetics of rheumatoid arthritis (RA) began about four decades ago with the
discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci …
discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci …
Genetics of rheumatoid arthritis: underlying evidence of ethnic differences
Y Kochi, A Suzuki, R Yamada, K Yamamoto - Journal of autoimmunity, 2009 - Elsevier
A new age has begun in the genetics of rheumatoid arthritis (RA), as genome-wide association
studies scanning the human genome have been put into practical use. Among the RA-…
studies scanning the human genome have been put into practical use. Among the RA-…
Genetics of rheumatoid arthritis contributes to biology and drug discovery
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …
variants with diverse genomic and biological data sets to provide insight into …
Genetics of autoimmune diseases: perspectives from genome-wide association studies
Y Kochi - International immunology, 2016 - academic.oup.com
Genome-wide association studies (GWASs) for autoimmune diseases (ADs) have identified
many risk loci and have provided insights into the etiology of each disease. Some of these …
many risk loci and have provided insights into the etiology of each disease. Some of these …
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
S Tokuhiro, R Yamada, X Chang, A Suzuki, Y Kochi… - Nature …, 2003 - nature.com
Rheumatoid arthritis is a common inflammatory disease with complex genetic components.
We investigated the genetic contribution of the cytokine gene cluster in chromosome 5q31 to …
We investigated the genetic contribution of the cytokine gene cluster in chromosome 5q31 to …
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
The overwhelming majority of participants in current genetic studies are of European ancestry.
To elucidate disease biology in the East Asian population, we conducted a genome-wide …
To elucidate disease biology in the East Asian population, we conducted a genome-wide …
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
Rheumatoid arthritis is a common autoimmune disease with a complex genetic etiology. Here
we identify a SNP in the promoter region of FCRL3, a member of the Fc receptor-like family…
we identify a SNP in the promoter region of FCRL3, a member of the Fc receptor-like family…
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
Rheumatoid arthritis is a common autoimmune disease characterized by chronic inflammation.
We report a meta-analysis of genome-wide association studies (GWAS) in a Japanese …
We report a meta-analysis of genome-wide association studies (GWAS) in a Japanese …
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
Rheumatoid arthritis is a common autoimmune disease with a complex genetic etiology.
Here, through a genome-wide association study of rheumatoid arthritis, we identified a …
Here, through a genome-wide association study of rheumatoid arthritis, we identified a …
[PDF][PDF] Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases
…, H Tsunoda, Y Iwasaki, S Sumitomo, H Shoda, Y Kochi… - Cell, 2021 - cell.com
Genetic studies have revealed many variant loci that are associated with immune-mediated
diseases. To elucidate the disease pathogenesis, it is essential to understand the function of …
diseases. To elucidate the disease pathogenesis, it is essential to understand the function of …