Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis
…, Y Adachi, Y Maruyama, Y Shinomura - Experimental …, 2006 - journals.sagepub.com
Matrix metalloproteinase (MMP)-7, also known as matrilysin, is a “minimal domain MMP” that
exhibits proteolytic activity against components of the extracellular matrix (ECM). Matrilysin …
exhibits proteolytic activity against components of the extracellular matrix (ECM). Matrilysin …
[HTML][HTML] A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease
…, C Suzuki, Y Naishiro, H Yamamoto, Y Shinomura… - Modern …, 2006 - Springer
Mikulicz's disease (MD) has been included within the diagnosis of primary Sjögren's syndrome
(SS), but it represents a unique condition involving persistent enlargement of the lacrimal …
(SS), but it represents a unique condition involving persistent enlargement of the lacrimal …
[HTML][HTML] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer
…, K Imai, H Yamamoto, Y Shinomura - World journal of …, 2016 - ncbi.nlm.nih.gov
The human intestinal microbiome plays a major role in human health and diseases, including
colorectal cancer. Colorectal carcinogenesis represents a heterogeneous process with a …
colorectal cancer. Colorectal carcinogenesis represents a heterogeneous process with a …
Gain-of-Function Mutations of c-kit in Human Gastrointestinal Stromal Tumors
…, Y Matsuzawa, Y Kanakura, Y Shinomura, Y Kitamura - Science, 1998 - science.org
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the
human digestive tract, but their molecular etiology and cellular origin are unknown. …
human digestive tract, but their molecular etiology and cellular origin are unknown. …
Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors
…, K Isozaki, K Kinoshita, Y Shinomura, Y Kitamura - Gastroenterology, 2003 - Elsevier
Background & Aims : Most gastrointestinal stromal tumors (GISTs) have gain-of-function
mutations of c-kit receptor tyrosine kinase (KIT) gene, but some GISTs do not. We investigated …
mutations of c-kit receptor tyrosine kinase (KIT) gene, but some GISTs do not. We investigated …
Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders
…, M Yamamoto, H Takahashi, Y Shinomura… - Annals of the …, 2009 - ard.bmj.com
Background: Mikulicz’s disease (MD) has been considered as one manifestation of Sjögren’s
syndrome (SS). Recently, it has also been considered as an IgG 4 -related disorder. …
syndrome (SS). Recently, it has also been considered as an IgG 4 -related disorder. …
Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
…, Y Sasaki, R Maruyama, K Imai, Y Shinomura… - Cancer research, 2008 - AACR
Altered expression of microRNA (miRNA) is strongly implicated in cancer, and recent studies
have shown that, in cancer, expression of some miRNAs cells is silenced in association …
have shown that, in cancer, expression of some miRNAs cells is silenced in association …
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
…, Y Okamoto, S Kihara, J Miyagawa, Y Shinomura… - Gastroenterology, 2003 - Elsevier
Background & Aims : Obesity is one of the risk factors for liver fibrosis, in which plasma
adiponectin, an adipocytokine, levels are decreased. Hepatic stellate cells play central roles in …
adiponectin, an adipocytokine, levels are decreased. Hepatic stellate cells play central roles in …
Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
…, T Tokino, K Hirata, K Imai, M Toyota, Y Shinomura - Cancer research, 2012 - AACR
Large intergenic noncoding RNAs (lincRNA) have been less studied than miRNAs in cancer,
although both offer considerable theranostic potential. In this study, we identified frequent …
although both offer considerable theranostic potential. In this study, we identified frequent …
Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with …
…, K Hokari, H Tsukagoshi, Y Shinomura… - Gastrointestinal …, 2010 - Elsevier
BACKGROUND: Endoscopic submucosal dissection (ESD) was originally developed in Japan
for en bloc resection of gastric neoplasms. OBJECTIVE: To clarify whether the novel ESD …
for en bloc resection of gastric neoplasms. OBJECTIVE: To clarify whether the novel ESD …