Anti-HMGCR antibodies as a biomarker for immune-mediated necrotizing myopathies: A history of statins and experience from a large international multi-center study

…, MY Choi, MJ Fritzler, H Schmeling, Y Muro… - Autoimmunity …, 2016 - Elsevier
In an effort to find naturally occurring substances that reduce cholesterol by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme
A reductase (HMGCR), statins were first discovered by Endo …

Cutaneous manifestations in dermatomyositis: key clinical and serological features—a comprehensive review

Y Muro, K Sugiura, M Akiyama - Clinical reviews in allergy & immunology, 2016 - Springer
Dermatomyositis (DM) is a common idiopathic inflammatory myopathy. The pathogenesis is
considered to be microangiopathy affecting skin and muscle. The cutaneous manifestations …

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite.

H Masumoto, H Masukata, Y Muro, N Nozaki… - The Journal of cell …, 1989 - rupress.org
We report the interaction between a human centromere antigen and an alphoid DNA, a
human centromeric satellite DNA, which consists of 170-bp repeating units. A cloned alphoid …

[HTML][HTML] A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

…, Y Gotoh, K Irie, T Kano, K Shirakabe, Y Muro… - Journal of Biological …, 1996 - ASBMB
A cDNA encoding a novel member of the mitogen-activated protein kinase kinase (MAPKK)
family, MAPKK6, was isolated and found to encode a protein of 334 amino acids, with a …

Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study

…, A Furusaki, H Tanabe, S Sasaoka, Y Muro… - Archives of …, 2011 - jamanetwork.com
Objective To clarify the association of clinical and prognostic features with dermatomyositis (DM)-specific
autoantibodies (Abs) in adult Japanese patients with DM. Design Retrospective …

Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists

…, Y Kawaguchi, M Jinnin, Y Muro… - Modern …, 2019 - academic.oup.com
Although rheumatologists, neurologists and dermatologists see patients with polymyositis (PM)
and dermatomyositis (DM), their management appears to vary depending on the …

[HTML][HTML] The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist

…, Y Ito, T Takeichi, M Kono, Y Ogawa, Y Muro… - Journal of Investigative …, 2013 - Elsevier
Generalized pustular psoriasis (GPP) is a rare inflammatory skin disease that can be life-threatening.
Recently, it has been reported that familial GPP is caused by homozygous or …

Anti-MDA5 and anti-TIF1-γ antibodies have clinical significance for patients with dermatomyositis

K Hoshino, Y Muro, K Sugiura, Y Tomita… - …, 2010 - academic.oup.com
Objectives. Myositis-specific autoantibodies are useful for diagnosing PM/DM. Recently, two
new myositis-specific autoantibodies against melanoma differentiation-associated gene 5 (…

Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions

RL Ochs, Y Muro, Y Si, H Ge, EKL Chan… - Journal of allergy and …, 2000 - Elsevier
Background: Sera of patients with atopic dermatitis (AD) were found to have autoantibodies
that reacted with tissue culture cell substrates in immunohistochemistry to display a …

Anti‐DFS70 antibodies in 597 healthy hospital workers

…, EM Tan, Y Takasaki, Y Tomita, Y Muro - Arthritis & …, 2004 - Wiley Online Library
… The correlation between the IIF titers (x-axis) and the ELISA titers (y-axis) was significant (r
= 0.556, P < 0.001). The slope of the correlation line was expressed as y = 0.46 + 0.24x, with x …