Potassium ion recycling pathway via gap junction systems in the mammalian cochlea and its interruption in hereditary nonsyndromic deafness
T Kikuchi, JC Adams, Y Miyabe, E So… - Medical electron …, 2000 - Springer
In the mammalian cochlea, there are two independent gap junction systems, the epithelial
cell gap junction system and the connective tissue cell gap junction system. Thus far, four …
cell gap junction system and the connective tissue cell gap junction system. Thus far, four …
The critical role of C5a as an initiator of neutrophil-mediated autoimmune inflammation of the joint and skin
The deposition of IgG autoantibodies in peripheral tissues and the subsequent activation of
the complement system, which leads to the accumulation of the anaphylatoxin C5a in these …
the complement system, which leads to the accumulation of the anaphylatoxin C5a in these …
How to detect eosinophil ETosis (EETosis) and extracellular traps
…, Y Miyabe, C Furutani, T Saga, Y Moritoki… - Allergology …, 2021 - jstage.jst.go.jp
Eosinophils are short-lived and comprise only a small population of circulating leukocytes;
however, they play surprisingly multifunctional roles in homeostasis and various diseases …
however, they play surprisingly multifunctional roles in homeostasis and various diseases …
[HTML][HTML] Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis
…, Y Miyabe, A Takayasu, S Fukuda, C Miyabe… - Arthritis research & …, 2011 - Springer
Introduction Chemerin is a chemotactic agonist identified as a ligand for ChemR23 that is
expressed on macrophages and dendritic cells (DCs). In this study, we analyzed the …
expressed on macrophages and dendritic cells (DCs). In this study, we analyzed the …
[PDF][PDF] Astrocyte-and neuron-derived CXCL1 drives neutrophil transmigration and blood-brain barrier permeability in viral encephalitis
BD Michael, L Bricio-Moreno, EW Sorensen, Y Miyabe… - Cell reports, 2020 - cell.com
Herpes simplex virus (HSV)-1 encephalitis has significant morbidity partly because of an
over-exuberant immune response characterized by leukocyte infiltration into the brain and …
over-exuberant immune response characterized by leukocyte infiltration into the brain and …
Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver
H Ohara, Y Miyabe, Y Deyashiki, K Matsuura… - Biochemical …, 1995 - Elsevier
In this study, we compared the enzymatic reduction of 10 drugs with a ketone group by
homogeneous carbonyl reductase, aldehyde reductase and three dihydrodiol dehydrogenases of …
homogeneous carbonyl reductase, aldehyde reductase and three dihydrodiol dehydrogenases of …
Multi-institutional validation study of commercially available deformable image registration software for thoracic images
Purpose To assess the accuracy of the commercially available deformable image registration
(DIR) software for thoracic images at multiple institutions. Methods and Materials Thoracic 4…
(DIR) software for thoracic images at multiple institutions. Methods and Materials Thoracic 4…
[HTML][HTML] Angiotensin I Converting Enzyme Inhibitory Peptides Derived from Phycobiliproteins of Dulse Palmaria palmata
T Furuta, Y Miyabe, H Yasui, Y Kinoshita, H Kishimura - Marine drugs, 2016 - mdpi.com
We examined the inhibitory activity of angiotensin I converting enzyme (ACE) in protein
hydrolysates from dulse, Palmaria palmata. The proteins extracted from dulse were mainly …
hydrolysates from dulse, Palmaria palmata. The proteins extracted from dulse were mainly …
[HTML][HTML] Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis
…, W Yokoyama, C Miyabe, Y Miyabe… - BMC musculoskeletal …, 2014 - Springer
Background Some of cannabinoids, which are chemical compounds contained in marijuana,
are immunosuppressive. One of the receptors, CB receptor 1 (CB 1 ), is expressed …
are immunosuppressive. One of the receptors, CB receptor 1 (CB 1 ), is expressed …
Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex–induced arthritis
Y Miyabe, C Miyabe, TT Murooka, EY Kim… - Science …, 2017 - science.org
The deposition of immune complexes (ICs) in tissues induces a “type III hypersensitivity”
that results in tissue damage and underlies the pathogenesis of many autoimmune diseases. …
that results in tissue damage and underlies the pathogenesis of many autoimmune diseases. …