User profiles for Y. Lo

Yu-Hwa Lo

- Y. Lo - Verified email at ucsd.edu - Cited by 19545

Yu-Chih Lo Ph.D.

- Verified email at ncku.edu.tw - Cited by 4379

Yu-Chen Lo

- Verified email at stanford.edu - Cited by 1518

[HTML][HTML] Machine learning in chemoinformatics and drug discovery

YC Lo, SE Rensi, W Torng, RB Altman - Drug discovery today, 2018 - Elsevier
Lo et al. developed the ShapeAlign program that combines 2D and 3D metrics based on
the Obabel PF2 fingerprint, shapes and pharmacophoric points for unsupervised 3D chemical …

Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies

YMD Lo, DSC Han, P Jiang, RWK Chiu - Science, 2021 - science.org
… -specific or disease-related cell-free DNA molecules, the first approaches to liquid biopsies
were based on the analysis of genetic variations between individuals [for example, the Y

The death domain superfamily in intracellular signaling of apoptosis and inflammation

HH Park, YC Lo, SC Lin, L Wang, JK Yang… - Annu. Rev …, 2007 - annualreviews.org
The death domain (DD) superfamily comprising the death domain (DD) subfamily, the death
effector domain (DED) subfamily, the caspase recruitment domain (CARD) subfamily, and …

Presence of fetal DNA in maternal plasma and serum

YMD Lo, N Corbetta, PF Chamberlain, V Rai… - The lancet, 1997 - thelancet.com
… DNA from plasma, serum, and nucleated blood cells from 43 pregnant women underwent a
sensitive Y-PCR assay to detect circulating male fetal DNA from women bearing male fetuses…

ZnO nanowire UV photodetectors with high internal gain

…, SA Dayeh, DPR Aplin, J Park, XY Bao, YH Lo… - Nano …, 2007 - ACS Publications
ZnO nanowire (NW) visible-blind UV photodetectors with internal photoconductive gain as
high as G ∼ 10 8 have been fabricated and characterized. The photoconduction mechanism …

Theory and experiment on microstrip antennas

Y Lo, D Solomon, W Richards - IEEE transactions on Antennas …, 1979 - ieeexplore.ieee.org
A simple theory based on the cavity model is developed to analyze microstrip antennas.
Formulas for numerous canonical shapes are given. In general the theoretically predicted …

Testing the number of components in a normal mixture

Y Lo, NR Mendell, DB Rubin - Biometrika, 2001 - academic.oup.com
We demonstrate that, under a theorem proposed by Vuong, the likelihood ratio statistic based
on the Kullback–Leibler information criterion of the null hypothesis that a random sample …

[PDF][PDF] Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis

YMD Lo, MSC Tein, TK Lau, CJ Haines… - The American Journal of …, 1998 - cell.com
We have developed a real-time quantitative PCR assay to measure the concentration of
fetal DNA in maternal plasma and serum. Our results show that fetal DNA is present in high …

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma

RWK Chiu, KCA Chan, Y Gao… - Proceedings of the …, 2008 - National Acad Sciences
Chromosomal aneuploidy is the major reason why couples opt for prenatal diagnosis.
Current methods for definitive diagnosis rely on invasive procedures, such as chorionic villus …

Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus

YMD Lo, KCA Chan, H Sun, EZ Chen, P Jiang… - Science translational …, 2010 - science.org
Cell-free fetal DNA is present in the plasma of pregnant women. It consists of short DNA
fragments among primarily maternally derived DNA fragments. We sequenced a maternal …