Objective: To assess the efficacy and safety of 100 mg daily anakinra (Kineret), a recombinant
form of the naturally occurring interleukin 1 receptor antagonist, plus methotrexate (MTX) …

Objective To assess the safety of rituximab in combination with a tumor necrosis factor (TNF)
inhibitor and methotrexate (MTX) in patients with rheumatoid arthritis (RA). Methods Adult …

Purpose: Beginning in the 1980s, methotrexate has been used successfully to treat
rheumatoid arthritis. The magnitude and severity of short- and long-term methotrexate toxicity, …

OBJECTIVE: To assess the timing of onset of clinical benefit following the initial infusion of
infliximab and to obtain additional safety experience of infliximab when given in an office …

OBJECTIVE: To compare the effects on back pain of teriparatide versus alendronate, we
analyzed the reporting of back pain in a head to head comparator trial and a followup study. …

A 15-year-old boy had bilateral idiopathic orbital inflammation refractory to treatment with
corticosteroids. He was not only unresponsive to subsequent therapy with methotrexate but …

An additional disorder in the spectrum of thyroid related muscle disease is presented.
Hypothyroid and hyperthyroid disease are both associated with a variety of muscle abnormalities, …

OBJECTIVES: To highlight the importance of improving quality of life (QoL) in patients with
rheumatoid arthritis (RA) and to provide a summary of the QoL benefits provided by abatacept …

• Four adult patients with unstable angina were treated with intravenous nitroglycerin in the
coronary intensive care unit. All four patients experienced an acute gouty flare while …

The Effectiveness of Discontinuing Bisphosphonates (EDGE) study is a planned pragmatic
clinical trial to guide “drug holiday” clinical decision making. This pilot study assessed work …