User profiles for William D. Leslie
william leslieprofessor of medicine, university of manitoba Verified email at sbgh.mb.ca Cited by 36573 |
[HTML][HTML] 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary
…, SM Kaiser, B Kvern, K Siminoski, WD Leslie - Cmaj, 2010 - Can Med Assoc
Since the publication of the Osteoporosis Canada guide-lines in 2002, there has been a
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus now …
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus now …
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
…, JM Koh, P Kollia, BL Langdahl, WD Leslie… - Nature …, 2012 - nature.com
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …
Trabecular bone score: a noninvasive analytical method based upon the DXA image
The trabecular bone score (TBS) is a gray‐level textural metric that can be extracted from
the two‐dimensional lumbar spine dual‐energy X‐ray absorptiometry (DXA) image. TBS is …
the two‐dimensional lumbar spine dual‐energy X‐ray absorptiometry (DXA) image. TBS is …
Interpretation and use of FRAX in clinical practice
The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture risk
on the basis of fracture probability. Its use in fracture risk prediction has strengths, but also …
on the basis of fracture probability. Its use in fracture risk prediction has strengths, but also …
A meta‐analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX
Trabecular bone score (TBS) is a gray‐level textural index of bone microarchitecture derived
from lumbar spine dual‐energy X‐ray absorptiometry (DXA) images. TBS is a bone mineral …
from lumbar spine dual‐energy X‐ray absorptiometry (DXA) images. TBS is a bone mineral …
Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: the Manitoba study
…, AL Goertzen, MA Krieg, WD Leslie - Journal of Bone and …, 2011 - academic.oup.com
… William D Leslie William D Leslie … Hans and MA Krieg were completely blind to the
clinical data until the analysis were finalized by WD Leslie. …
clinical data until the analysis were finalized by WD Leslie. …
Use of proton pump inhibitors and risk of osteoporosis-related fractures
Background: The use of proton pump inhibitors has been associated with an increased risk
of hip fracture. We sought to further explore the relation between duration of exposure to …
of hip fracture. We sought to further explore the relation between duration of exposure to …
A meta‐analysis of the association of fracture risk and body mass index in women
…, E Lau, WD Leslie, D Mellström… - Journal of bone and …, 2014 - academic.oup.com
Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this
study was to investigate the association between body mass index (BMI) and future fracture …
study was to investigate the association between body mass index (BMI) and future fracture …
AGA technical review on osteoporosis in gastrointestinal diseases
CN Bernstein, WD Leslie, MS Leboff - Gastroenterology, 2003 - Elsevier
Osteoporosis is increasingly recognized as a source of significant disability, an awareness
that has prompted clinicians to actively pursue the diagnosis among high-risk patients. …
that has prompted clinicians to actively pursue the diagnosis among high-risk patients. …
Trends in hip fracture rates in Canada
WD Leslie, S O'Donnell, S Jean, C Lagacé, P Walsh… - Jama, 2009 - jamanetwork.com
Context Hip fractures are a public health concern because they are associated with
significant morbidity, excess mortality, and the majority of the costs directly attributable to …
significant morbidity, excess mortality, and the majority of the costs directly attributable to …