Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
Drug resistance during chemotherapy is the major obstacle to the successful treatment of
many cancers. Here, we report that inhibition of NF-E2-related factor 2 (Nrf2) may be a …
many cancers. Here, we report that inhibition of NF-E2-related factor 2 (Nrf2) may be a …
[HTML][HTML] Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
Radiotherapy induces and promotes innate and adaptive immunity in which host STING
plays an important role. However, radioresistance in irradiated tumors can also develop, …
plays an important role. However, radioresistance in irradiated tumors can also develop, …
High levels of Nrf2 determine chemoresistance in type II endometrial cancer
Type II endometrial cancer, which mainly presents as serous and clear cell types, has
proved to be the most malignant and recurrent carcinoma among various female genital …
proved to be the most malignant and recurrent carcinoma among various female genital …
Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration
The clinical utility of stimulator of interferon genes (STING) agonists has been limited due to
poor tumour-targeting and unwanted toxicity following systemic delivery. Here we describe a …
poor tumour-targeting and unwanted toxicity following systemic delivery. Here we describe a …
Low-grade endometrial stromal sarcoma: hormonal aspects☆
MC Chu, G Mor, C Lim, W Zheng, V Parkash… - Gynecologic …, 2003 - Elsevier
OBJECTIVE: The goal of this work was to determine whether exposure to estrogen following
treatment of low-grade endometrial stromal sarcomas affects clinical outcome. METHODS: …
treatment of low-grade endometrial stromal sarcomas affects clinical outcome. METHODS: …
Randomized trial of intravenous versus intraperitoneal chemotherapy plus bevacizumab in advanced ovarian carcinoma: an NRG oncology/gynecologic oncology …
…, K Fujiwara, DS Alberts, W Zheng… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE To evaluate the impact of two different intraperitoneal (IP) chemotherapy
regimens on progression-free survival (PFS) among women with newly diagnosed advanced …
regimens on progression-free survival (PFS) among women with newly diagnosed advanced …
Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling
Y Shi, W Zheng, K Yang, KG Harris, K Ni… - Journal of Experimental …, 2020 - rupress.org
Most studies focus on how intestinal microbiota influence cancer immunotherapy through
activating gut immunity. However, immunotherapies related to innate responses such as CD47 …
activating gut immunity. However, immunotherapies related to innate responses such as CD47 …
The oncofetal protein IMP3: a novel biomarker for endometrial serous carcinoma
W Zheng, X Yi, O Fadare, SX Liang… - The American journal …, 2008 - journals.lww.com
Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein highly
expressed in fetal tissue and malignant tumors but rarely found in adult benign tissues. The aim …
expressed in fetal tissue and malignant tumors but rarely found in adult benign tissues. The aim …
Follicle-stimulating hormone receptor is expressed in human ovarian surface epithelium and fallopian tube.
W Zheng, MS Magid, EE Kramer… - The American journal of …, 1996 - ncbi.nlm.nih.gov
The cellular expression of pituitary gonadotropin receptors in gonadal tissues is poorly defined
because of the lack of suitable reagents. In this study, we developed in situ hybridization …
because of the lack of suitable reagents. In this study, we developed in situ hybridization …
[HTML][HTML] Tubal origin of 'ovarian'low-grade serous carcinoma
…, L Xiang, SK Chambers, O Fadare, B Kong, W Zheng - Modern Pathology, 2011 - Elsevier
Ovarian low-grade serous carcinomas are thought to evolve in a stepwise fashion from
ovarian epithelial inclusions, cystadenomas, and borderline tumors. The current study was …
ovarian epithelial inclusions, cystadenomas, and borderline tumors. The current study was …