User profiles for Walter Fierz

Walter Fierz

SVDI
Verified email at svdi.ch
Cited by 5074

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

A Fontana, W Fierz, H Wekerle - Nature, 1984 - nature.com
Astrocyte proliferation and perivascular lymphocyte infiltration are conspicuous among the
cellular changes in the active brain lesions of multiple sclerosis patients 1 . Recent …

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

W Fierz, B Endler, K Reske, H Wekerle… - Journal of immunology …, 1985 - journals.aai.org
Ia antigens seem to control immune responses on at least two levels. First, they influence
the antigen recognition repertoire of the T cells. Second, their variable expression on certain …

[HTML][HTML] Interpretation of erythropoietin levels in patients with various degrees of renal insufficiency and anemia

T Fehr, P Ammann, D Garzoni, W Korte, W Fierz… - Kidney international, 2004 - Elsevier
… Author links open overlay panel Thomas Fehr , Peter Ammann , Daniela Garzoni ,
Wolfgang Korte , Walter Fierz , Hans Rickli , Rudolf P. Wüthrich …

[HTML][HTML] Antibody dependent enhancement due to original antigenic sin and the development of SARS

W Fierz, B Walz - Frontiers in immunology, 2020 - frontiersin.org
Human coronavirus (HCoV) is one of the most common causes of respiratory tract infections
throughout the world. Two phenomena observed so far in the development of the SARS-CoV…

Statin-induced immunomodulatory effects on human T cells in vivo

T Fehr, C Kahlert, W Fierz, HI Joller-Jemelka… - Atherosclerosis, 2004 - Elsevier
Statins are widely used for treatment of hypercholesterolemia. Recent experimental studies
revealed that these drugs also exert anti-inflammatory effects. The aim of this study was to …

[HTML][HTML] Multiple sclerosis: an example of pathogenic viral interaction?

W Fierz - Virology journal, 2017 - Springer
A hypothesis is formulated on viral interaction between HHV-6A and EBV as a pathogenic
mechanism in Multiple Sclerosis (MS). Evidence of molecular and genetic mechanisms …

[PDF][PDF] Challenge of personalized health care: to what extent is medicine already individualized and what are the future trends

W Fierz - Med Sci Monit, 2004 - academia.edu
Personalized medicine: is it hype or revolution? In any case, there is not only real demand
for it, but it also has a history. As it is, the personal aspects of health care have been partly …

[HTML][HTML] Detection of antinuclear antibodies: recommendations from EFLM, EASI and ICAP

C Bonroy, M Vercammen, W Fierz… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Antinuclear antibodies (ANA) are important for the diagnosis of various autoimmune
diseases. ANA are usually detected by indirect immunofluorescence assay (IFA) using …

The role of compartment penetration in PI-monotherapy: the Atazanavir-Ritonavir Monomaintenance (ATARITMO) Trial

P Vernazza, S Daneel, V Schiffer, L Decosterd, W Fierz… - Aids, 2007 - journals.lww.com
Objectives: To limit exposure to anti-HIV drugs and minimize risk of long-term side effects,
studies have looked at the possibility of simplified maintenance strategies. Ritonavir-boosted …

[HTML][HTML] Likelihood ratio approach and clinical interpretation of laboratory tests

W Fierz, X Bossuyt - Frontiers in Immunology, 2021 - frontiersin.org
Laboratory tests are an important component in the diagnostic process. From an analytical
point of view, most tests have reached high technical standards resulting in quantitative …