In spite of substantial efforts by many investigators as well as numerous publications on the
subject, the nomenclature of the systemic vasculitides remains enigmatic. A major problem is …

Objectives: To develop the European League Against Rheumatism (EULAR) recommendations
for conducting clinical studies and/or clinical trials in systemic vasculitis. Methods: An …

Objectives: We undertook a systematic literature review as a background to the European
League Against Rheumatism (EULAR) recommendations for conducting clinical trials in anti-…

Small-vessel vasculitis (SVV) is a chronic autoinflammatory condition linked to
antineutrophil cytoplasm autoantibodies (ANCAs). Here we show that chromatin fibers, so-called …

Objective Standard therapy for antineutrophil cytoplasmic antibody–associated systemic
vasculitis (AASV) with cyclophosphamide (CYC) and prednisolone is limited by toxicity. This …

Background Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a severe
condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly …

Background: Current therapies for antineutrophil cytoplasmic antibody (ANCA)–associated
vasculitis are limited by toxicity. Objective: To compare pulse cyclophosphamide with daily …

… Steppat D, Gross WL. Stage-adapted treatment of Wegener’s granulomatosis. Klin … De
Groot K, Mühler M, Reinhold-Keller E, Paulsen J, Gross WL. Induction of remission in Wegener’s …

Study Objective: To determine disease specificity and sensitivity of anticytoplasmic
autoantibodies (ACPA) for Wegener granulomatosis, as well as their value as a marker of disease …

The Boards of Directors of the American College of Rheumatology (ACR), American Society
of Nephrology (ASN) and the European League Against Rheumatism (EULAR) have …