FRI0421 A randomised, double-blind, parallel-group, phase 1 study comparing the pharmacokinetics, safety and efficacy of ct-p13 and infliximab in patients with active …

…, C Abud-Mendoza, WJO Escalante… - Annals of the …, 2013 - ard.bmj.com
Background CT-P13 is a biosimilar product of infliximab (INX). Data up to week 30 has been
reported at EULAR 2012. Objectives To assess the PK, efficacy and safety of CT-P13 in …

Tofacitinib in combination with methotrexate in patients with rheumatoid arthritis: clinical efficacy, radiographic, and safety outcomes from a twenty‐four–month, phase …

…, MH Cardiel‐Rios, WJO Escalante… - Arthritis & …, 2019 - Wiley Online Library
Objective Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis ( RA ).
The phase III , 24‐month, placebo‐controlled Oral Rheumatoid Arthritis ( ORAL ) Scan trial …

[HTML][HTML] Bacterial incidence and drug resistance from pathogens recovered from blood, cerebrospinal and pleural fluids in 2019–2020. Results of the Invifar network

…, A Molina, SP Escalante-Armenta… - PeerJ, 2023 - peerj.com
… RA, Molina A, Escalante-Armenta SP, Duarte L, Ruiz-Gamboa LA, Cobos-Canul DI, López
D, Barroso-Herrera-y-Cairo IE, Rodriguez-Noriega E, Morfin-Otero R. Bacterial incidence and …

Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom

JM Gutiérrez, T Escalante, A Rucavado - Toxicon, 2009 - Elsevier
Moderate and severe envenomations by the snake Bothrops asper provoke systemic alterations,
such as systemic bleeding, coagulopathy, hypovolemia, hemodynamic instability and …

Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase …

T Escalante, A Franceschi, A Rucavado… - Biochemical …, 2000 - Elsevier
Batimastat (BB-94), a synthetic hydroxamate peptidomimetic matrix metalloproteinase
inhibitor, was tested for its ability to inhibit proteolytic and toxic effects induced by BaP1, a 24-kDa …

Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins

T Escalante, A Rucavado, AFM Pinto… - Journal of proteome …, 2009 - ACS Publications
In light of the complexity of wound tissue, proteomic analysis may not clearly reveal the
nature of the wound or the processes involved in healing. However, exudate associated with …

A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in …

W Park, P Hrycaj, S Jeka, V Kovalenko… - Annals of the …, 2013 - ard.bmj.com
Objectives To compare the pharmacokinetics (PK), safety and efficacy of innovator infliximab
(INX) and CT-P13, a biosimilar to INX, in patients with active ankylosing spondylitis (AS). …

A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when …

DH Yoo, P Hrycaj, P Miranda, E Ramiterre… - Annals of the …, 2013 - ard.bmj.com
Objectives To compare the efficacy and safety of innovator infliximab (INX) and CT-P13, an
INX biosimilar, in active rheumatoid arthritis patients with inadequate response to …

[HTML][HTML] MDR-1 and MRP2 gene polymorphisms in Mexican epileptic pediatric patients with complex partial seizures

D Escalante-Santiago, IA Feria-Romero… - Frontiers in …, 2014 - frontiersin.org
Although the Pgp efflux transport protein is overexpressed in resected tissue of patients with
epilepsy, the presence of polymorphisms in MDR1/ABCB1 and MRP2/ABCC2 in patients …

Reproduction, abundance and feeding habits of the broadnose sevengill shark Notorynchus cepedianus in north Patagonia, Argentina

LO Lucifora, RC Menni, AH Escalante - Marine Ecology progress series, 2005 - int-res.com
Broadnose sevengill sharks Notorynchus cepedianus caught in a recreational fishery during
a 3 yr period in Anegada Bay, Argentina were examined. Monthly variations in abundance …