Inhibition of T lymphocyte mitogenesis by 1, 25-dihydroxyvitamin D3 (calcitriol).
WF Rigby, T Stacy, MW Fanger - The Journal of clinical …, 1984 - Am Soc Clin Investig
Recent studies have suggested that vitamin D may have other important biologic activities in
addition to its well-characterized role in the maintenance of calcium homeostasis. Discovery …
addition to its well-characterized role in the maintenance of calcium homeostasis. Discovery …
Regulation of lymphokine production and human T lymphocyte activation by 1, 25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA.
WF Rigby, S Denome, MW Fanger - The Journal of clinical …, 1987 - Am Soc Clin Investig
The steroid hormone, 1 alpha,25-dihydroxyvitamin D3 (calcitriol), has been shown to inhibit
T cell proliferation, primarily through inhibition of interleukin 2 (IL-2) production. In these …
T cell proliferation, primarily through inhibition of interleukin 2 (IL-2) production. In these …
Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid …
Objectives This phase III study evaluated the efficacy and safety of rituximab plus methotrexate
(MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response …
(MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response …
Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial
PP Tak, WF Rigby, A Rubbert-Roth… - Annals of the …, 2011 - ard.bmj.com
Objectives Rituximab is an effective treatment in patients with established rheumatoid arthritis
(RA). The objective of the IMAGE study was to determine the efficacy of rituximab in the …
(RA). The objective of the IMAGE study was to determine the efficacy of rituximab in the …
Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma, and IL-3.
EJ Gosselin, K Wardwell, WF Rigby… - Journal of immunology …, 1993 - journals.aai.org
Polymorphonuclear neutrophils (PMN) have long been thought to be short-lived, terminally
differentiated cells incapable of synthesizing significant levels of protein, with their primary …
differentiated cells incapable of synthesizing significant levels of protein, with their primary …
Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial
GR Burmester, WF Rigby… - Annals of the …, 2016 - ard.bmj.com
Objectives The efficacy of tocilizumab (TCZ), an anti-interleukin-6 receptor antibody, has not
previously been evaluated in a population consisting exclusively of patients with early …
previously been evaluated in a population consisting exclusively of patients with early …
[PDF][PDF] The safety and immunogenicity of live zoster vaccination in patients with rheumatoid arthritis before starting tofacitinib: a randomized phase II trial
…, S Passador, CF Mojcik, WF Rigby - Arthritis & …, 2017 - Wiley Online Library
… Rigby has received consulting fees from Pfizer (less than $10,000). Address correspondence
to Kevin L. Winthrop, MD, MPH, Casey Eye Institute, Oregon Health and Science University…
to Kevin L. Winthrop, MD, MPH, Casey Eye Institute, Oregon Health and Science University…
[HTML][HTML] Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.
…, E Nagy, JS Malter, BA Arrick, WF Rigby - Journal of Biological …, 1993 - Elsevier
Post-transcriptional regulatory mechanisms have been shown to play a major role in gene
expression in eukaryotic cells. The presence of a reiterated pentamer (AUUUA) in the 3'-…
expression in eukaryotic cells. The presence of a reiterated pentamer (AUUUA) in the 3'-…
Regulation of human monocyte HLA-DR and CD4 antigen expression, and antigen presentation by 1, 25-dihydroxyvitamin D3
WF Rigby, M Waugh, RF Graziano - 1990 - ashpublications.org
25-Dihydroxyvitamin D3 (1,25(OH)2-D) has been shown to be a macrophage-derived cytokine,
capable of regulating myeloid differentiation and T-cell activation in vitro. Therefore, we …
capable of regulating myeloid differentiation and T-cell activation in vitro. Therefore, we …
Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and …
GR Burmester, WF Rigby… - Annals of the …, 2017 - ard.bmj.com
Objective Investigate whether the efficacy and safety of intravenous tocilizumab (TCZ)
demonstrated at week 52 in patients with early rheumatoid arthritis (RA) are maintained to week …
demonstrated at week 52 in patients with early rheumatoid arthritis (RA) are maintained to week …