New biomarker evidence of oxidative DNA damage in patients with non‐insulin‐dependent diabetes mellitus

…, H Hiai, H Ochi, P Laippala, V Rantalaiho… - FEBS …, 1997 - Wiley Online Library
Urinary 8‐hydroxy‐2′‐deoxyguanosine (8‐OHdG) has been reported to serve as a sensitive
biomarker of oxidative DNA damage and also of oxidative stress. We have investigated …

Infections of the central nervous system of suspected viral origin: a collaborative study from Finland

M Koskiniemi, T Rantalaiho, H Piiparinen… - Journal of …, 2001 - Springer
We studied 3231 patients with acute central nervous system (CNS) symptoms of suspected
viral origin to elucidate the current etiologic spectrum. In 46% of the cases, a viral finding was …

Beneficial effect of interleukin 1 inhibition with anakinra in adult-onset Still's disease. An open, randomized, multicenter study

…, R van Vollenhoven, V Rantalaiho… - The Journal of …, 2012 - jrheum.org
Objective. To study the efficacy of anakinra versus disease-modifying antirheumatic drugs (DMARD)
in refractory adult-onset Still’s disease (AOSD). Methods. In a 24-week study, 22 …

[HTML][HTML] Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early …

V Rantalaiho, M Korpela, L Laasonen… - Arthritis research & …, 2010 - Springer
Introduction Early treatment of rheumatoid arthritis (RA) has been shown to retard the development
of joint damage for a period of up to 5 years. The aim of this study was to evaluate the …

Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of …

…, T Lehtimäki, J Laakso, I Ruokonen, V Rantalaiho… - Metabolism, 2003 - Elsevier
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS).
Increased plasma levels of ADMA may indicate endothelial dysfunction and increased …

Acute central nervous system complications in varicella zoster virus infections

M Koskiniemi, H Piiparinen, T Rantalaiho… - Journal of clinical …, 2002 - Elsevier
Background: In a previous multicenter study on central nervous system (CNS) viral infections
varicella zoster virus (VZV) appeared the most frequent etiologic agent and appeared often …

The good initial response to therapy with a combination of traditional disease‐modifying antirheumatic drugs is sustained over time: the eleven‐year results of the …

V Rantalaiho, M Korpela, P Hannonen… - Arthritis & …, 2009 - Wiley Online Library
Objective To evaluate the evolution of functional and clinical outcomes over 11 years in
patients with early rheumatoid arthritis (RA) initially treated with a combination of 3 disease‐…

[BOOK][B] Gendered practices in working life

L Rantalaiho, T Heiskanen, J Campling - 1997 - Springer
We are grateful to a number of people and organisations for their support. This book is an
outcome of a cooperative effort. That the research group had the opportunity to work together …

Treatment of displaced olecranon fractures: a systematic review

IK Rantalaiho, AE Miikkulainen… - … Journal of Surgery, 2021 - journals.sagepub.com
Background and Aims: The incidence of olecranon fractures is rising. Displaced fractures are
usually operated either by tension band wiring or plate fixation. The aim of this review is to …

Rates of serious infections and malignancies among patients with rheumatoid arthritis receiving either tumor necrosis factor inhibitor or rituximab therapy

…, P Aronen, H Relas, H Valleala, V Rantalaiho… - The Journal of …, 2015 - jrheum.org
Objective. Because of the role of tumor necrosis factor (TNF) in host defense, it was hypothesized
that its inhibition might lead to an increased risk of malignancies and infections. The …