Background A substantial number of patients with rheumatoid arthritis have an inadequate
or unsustained response to tumor necrosis factor α (TNF-α) inhibitors. We conducted a …

Background: The selective co-stimulation modulator abatacept demonstrated efficacy for
treating rheumatoid arthritis in early clinical studies. Objective: To evaluate the effects of …

Objective To determine the clinical efficacy, safety, and immunogenicity of abatacept (CTLA‐4Ig),
a selective costimulation modulator, in patients with rheumatoid arthritis (RA) that has …

Objective: To investigate the efficacy and safety of abatacept in combination with etanercept
in patients with active rheumatoid arthritis during a 1-year, randomised, placebo-controlled, …

The geometric structure of a single-particle energy band in a solid is fundamental for a wide
range of many-body phenomena and is uniquely characterized by the distribution of Berry …

This study evaluated the use of walking speed as an indicator of function and health status
in acutely ill, hospitalized, older male veterans. Hospital inpatients in a Department of …

OBJECTIVE: Except for some polysomnography studies, there have been no large quantitative
studies of sleep disturbance (SD) in rheumatoid arthritis (RA). SD has taken on new …

Topology and geometry are essential to our understanding of modern physics, underlying
many foundational concepts from high-energy theories, quantum information, and condensed-…

We report direct observations of photon-mediated spin-exchange interactions in an atomic
ensemble. Interactions extending over a distance of 500 μ m are generated within a cloud of …

Objective To evaluate the efficacy, radiographic changes, and safety of abatacept and
methotrexate therapy through 2 years in a long‐term extension of a previously published 1‐year …