MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial …
…, P Junker, T Lottenburger… - Annals of the …, 2009 - ard.bmj.com
… Substantial efforts have been exerted to identify this subset of patients with a poor prognosis
at the time of diagnosis and several promising prognostic markers have been identified. …
at the time of diagnosis and several promising prognostic markers have been identified. …
Radiographic progression and remission rates in early rheumatoid arthritis–MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year …
…, BJ Ejbjerg, S Jacobsen, T Lottenburger… - Annals of the …, 2010 - ard.bmj.com
Objective At 5 years' follow-up of early (<6 months) rheumatoid arthritis patients to (1) investigate
whether initial combination therapy with methotrexate (MTX) and ciclosporin (CSA) (n=…
whether initial combination therapy with methotrexate (MTX) and ciclosporin (CSA) (n=…
Combination treatment with methotrexate, cyclosporine, and intraarticular betamethasone compared with methotrexate and intraarticular betamethasone in early …
…, P Junker, T Lottenburger… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To investigate whether disease control can be achieved in early active rheumatoid
arthritis (RA) by treatment with methotrexate and intraarticular betamethasone, and whether …
arthritis (RA) by treatment with methotrexate and intraarticular betamethasone, and whether …
Aggressive combination therapy with intra-articular glucocorticoid injections and conventional disease-modifying anti-rheumatic drugs in early rheumatoid arthritis …
…, P Junker, T Lottenburger… - Annals of the …, 2008 - ard.bmj.com
Objective: To investigate whether clinical and radiographic disease control can be achieved
and maintained in patients with early, active rheumatoid arthritis (RA) during the second …
and maintained in patients with early, active rheumatoid arthritis (RA) during the second …
Short-and long-term efficacy of intra-articular injections with betamethasone as part of a treat-to-target strategy in early rheumatoid arthritis: impact of joint area …
…, P Junker, T Lottenburger… - Annals of the …, 2012 - ard.bmj.com
Objective To investigate the short-term and long-term efficacy of intra-articular betamethasone
injections, and the impact of joint area, repeated injections, MRI pathology, anticyclic …
injections, and the impact of joint area, repeated injections, MRI pathology, anticyclic …
Pre-analytical and biological variability in circulating interleukin 6 in healthy subjects and patients with rheumatoid arthritis
LS Knudsen, IJ Christensen, T Lottenburger… - Biomarkers, 2008 - Taylor & Francis
Interleukin (IL)-6, a key player in the inflammatory response, may be a useful biomarker in
rheumatoid arthritis (RA). The aim was to determine analytical variability, a reference interval …
rheumatoid arthritis (RA). The aim was to determine analytical variability, a reference interval …
Diurnal, weekly, and long-time variation in serum concentrations of YKL-40 in healthy subjects
JS Johansen, T Lottenburger, HJ Nielsen… - … Biomarkers & Prevention, 2008 - AACR
Serum YKL-40 is a potential biomarker of prognosis in cancer patients, but assessment of
serum YKL-40 requires knowledge of its normal variation. In this study, we evaluated diurnal, …
serum YKL-40 requires knowledge of its normal variation. In this study, we evaluated diurnal, …
Biological variation in circulating levels of mannan‐binding lectin (MBL) and MBL‐Associated serine protease‐2 and the influence of age, gender and physical …
…, L Nielsen, T Lottenburger… - Scandinavian …, 2007 - Wiley Online Library
Mannan‐binding lectin (MBL) and MBL‐associated serine protease 2 (MASP‐2) are central
components of the MBL pathway of complement activation, and may have potential as …
components of the MBL pathway of complement activation, and may have potential as …
Circulating VEGF as a biological marker in patients with rheumatoid arthritis? Preanalytical and biological variability in healthy persons and in patients
ML Hetland, IJ Christensen, T Lottenburger… - Disease …, 2008 - hindawi.com
Background: Soluble vascular endothelial growth factor (VEGF) is a promising biomarker in
monitoring rheumatoid arthritis (RA), but studies of pre-analytical and biologic variability are …
monitoring rheumatoid arthritis (RA), but studies of pre-analytical and biologic variability are …
Galectin‐3 is Persistently Increased in Early Rheumatoid Arthritis (RA) and Associates with Anti‐CCP Seropositivity and MRI Bone Lesions, While Early Fibrosis …
…, BJ Ejbjerg, T Lottenburger… - Scandinavian …, 2017 - Wiley Online Library
Galectin‐3 has been suggested as a pro‐inflammatory mediator in animal arthritis and
rheumatoid arthritis ( RA ). We aimed to study the serum level of galectin‐3 in patients with newly …
rheumatoid arthritis ( RA ). We aimed to study the serum level of galectin‐3 in patients with newly …