Development of effective pharmaceutical interventions in acquired immunodeficiency syndrome
(AIDS) is a high priority goal. About 10 million individuals worldwide are estimated to be …

Farnesyl:protein transferase (FPTase) inhibitors (FTIs) were originally developed as potential
anticancer agents targeting the ras oncogene and are currently in clinical trials. Whereas …

In this research study, we hear the voices of middle school students, preservice teachers,
and practicing middle school teachers in support of school-based experiential outdoor …

Background We assessed the effects of reduction and withdrawal of treatment in patients
with rheumatoid arthritis who had a remission while receiving etanercept-plus-methotrexate …

Opinions differ concerning the efficacy of prophylaxis against neonatal chlamydial and
gonococcal conjunctivitis. From January 1986 through June 1988, we gave all infants born at …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been shown to be a key
component of highly active antiretroviral therapy (HAART). The use of NNRTIs has become part …

Calcitonin gene-related peptide (CGRP) is a potent neuropeptide that plays a key role in the
pathophysiology of migraine headache. CGRP levels in the cranial circulation are …

Calcitonin gene-related peptide (CGRP) has been implicated in the pathogenesis of migraine.
Herein we describe optimization of CGRP receptor antagonists based on an earlier lead …

To test the hypothesis that diabetes mellitus is associated with cognitive dysfunction, a battery
of neuropsychological tests was administered to 75 diabetic adults and an equal number …

Previous work with elderly adults with maturity-onset non-insulin-dependent diabetes has
demonstrated the presence of significant learning and memory deficits which are correlated …