Objective STAT4 encodes a transcriptional factor that transmits signals induced by several
key cytokines, and it might be a key molecule in the development of autoimmune diseases. …

Aim To evaluate the prevalence rate and factors associated with sarcopenia in Japanese
patients with rheumatoid arthritis. Methods We enrolled 240 consecutive patients with …

Objective: To examine the deterioration of interstitial lung disease (ILD) in patients with
rheumatoid arthritis (RA) treated with abatacept over the long-term. Methods: We examined 131 …

Minimization of soft-tissue damage is one of the primary purposes behind the application of
minimally invasive surgery (MIS) in total knee arthroplasty (TKA). A consecutive series of 147 …

Background Foot and ankle joint disorders are serious issues for patients with rheumatoid
arthritis (RA). We compared the differences between patients with RA whose first symptom …

Background Recent advances in the understanding of blood coagulation processes favor
an inflammatory basis for thrombotic events. In this study, thrombotic risk after total knee …

The anti-TNF-α chimeric monoclonal antibody infliximab is the first biologic to be approved
for rheumatoid arthritis (RA) in Japan, and post-marketing surveillance of all of the Japanese …

Objectives To investigate effects of romosozumab treatment on disease activity and bone
mineral density (BMD) in patients with rheumatoid arthritis (RA) and severe osteoporosis in …

Objectives To investigate the effect of romosozumab versus denosumab treatment on bone
mineral density (BMD), disease activity, and joint damage in patients with rheumatoid arthritis …

We aimed to investigate the efficacy of denosumab for rheumatoid arthritis (RA). This study
enrolled 70 RA patients who received denosumab 60 mg subcutaneous injection at baseline …