Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk?

TE Toms, VF Panoulas, KMJ Douglas… - Annals of the …, 2010 - ard.bmj.com
Background Cardiovascular disease (CVD) is partially attributed to traditional cardiovascular
risk factors, which can be identified and managed based on risk stratification algorithms (…

Dyslipidaemia in rheumatoid arthritis: the role of inflammation, drugs, lifestyle and genetic factors

TE Toms, DP Symmons… - Current vascular …, 2010 - ingentaconnect.com
Rheumatoid arthritis (RA) associates with excess cardiovascular morbidity and mortality,
resulting in significantly shortened lifespan. Traditional risk factors (eg dyslipidaemia and …

[HTML][HTML] Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60-more than just an anti …

TE Toms, VF Panoulas, H John, KMJ Douglas… - Arthritis research & …, 2009 - Springer
Introduction The metabolic syndrome (MetS) may contribute to the excess cardiovascular
burden observed in rheumatoid arthritis (RA). The prevalence and associations of the MetS in …

[HTML][HTML] Dyslipidaemia in rheumatological autoimmune diseases

TE Toms, VF Panoulas, GD Kitas - The open cardiovascular …, 2011 - ncbi.nlm.nih.gov
Autoimmunity forms the basis of many rheumatological diseases, and may contribute not
only to the classical clinical manifestations but also to the complications. Many of the …

[HTML][HTML] Vascular function and inflammation in rheumatoid arthritis: the role of physical activity

…, A Sandoo, JJCSV van Zanten, TE Toms… - The open …, 2010 - ncbi.nlm.nih.gov
Inflammation disturbs biochemical pathways involved in homeostasis of the endothelium.
Research has established clear links between inflammatory mediators, particularly C-reactive …

Prolonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden

VF Panoulas, TE Toms, KMJ Douglas, A Sandoo… - …, 2014 - academic.oup.com
Objective. RA associates with an increased rate of sudden cardiac death (SCD). A prolonged
QTc interval has been associated with arrhythmogenic and SCD in patients with long QT …

Association of mean platelet volume with hypertension in rheumatoid arthritis

…, A Stavropoulos-Kalinoglou, TE Toms… - … & Allergy-Drug …, 2010 - ingentaconnect.com
Rheumatoid arthritis (RA) is one of the most common chronic inflammatory disorders associated
with enhanced cardiovascular morbidity and mortality. Established high prevalence of …

The rationale for comparative studies of accelerated atherosclerosis in rheumatic diseases

…, DP Mikhailidis, TE Toms… - Current vascular …, 2010 - ingentaconnect.com
The inflammatory pathogenesis of atherosclerosis is now well-established, owing to in vitro
and in vivo studies and the application of high sensitivity assays for C-reactive protein (CRP) …

Are lipid ratios less susceptible to change with systemic inflammation than individual lipid components in patients with rheumatoid arthritis?

TE Toms, VF Panoulas, KMJ Douglas… - …, 2011 - journals.sagepub.com
Rheumatoid arthritis (RA) associates with excess cardiovascular risk and there is a need to
assess that risk. However, individual lipid levels may be influenced by disease activity and …

Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis

…, I Antonopoulos, H John, TE Toms… - Annals of the …, 2010 - ard.bmj.com
Objectives The present study aimed to evaluate the prevalence and associations of renal
dysfunction in patients with rheumatoid arthritis (RA). It specifically addressed the hypotheses …