User profiles for TAKEHIRO TAKAHASHI

Takehiro Takahashi

Yale University School of Medicine, Department of Immunobiology
Verified email at yale.edu
Cited by 9078

[HTML][HTML] Sex differences in immune responses that underlie COVID-19 disease outcomes

T Takahashi, MK Ellingson, P Wong, B Israelow… - Nature, 2020 - nature.com
There is increasing evidence that coronavirus disease 2019 (COVID-19) produces more severe
symptoms and higher mortality among men than among women 1 , 2 , 3 , 4 – 5 . However…

[HTML][HTML] Longitudinal analyses reveal immunological misfiring in severe COVID-19

…, MK Ellingson, T Mao, JE Oh, B Israelow, T Takahashi… - Nature, 2020 - nature.com
Recent studies have provided insights into the pathogenesis of coronavirus disease 2019 (COVID-19)
1 , 2 , 3 – 4 . However, the longitudinal immunological correlates of disease …

[HTML][HTML] Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

…, JE Oh, A Park, J Silva, E Song, T Takahashi… - Nature …, 2020 - nature.com
The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exemplifies
the critical need for accurate and rapid diagnostic assays to prompt clinical and public …

Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: possible roles in scleroderma

T Takahashi, Y Asano, K Sugawara… - Journal of Experimental …, 2017 - rupress.org
Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disorder characterized
by vasculopathy and fibrosis in the skin and internal organs, most frequently in the …

[PDF][PDF] LINE-1 activation in the cerebellum drives ataxia

T Takahashi, M Stoiljkovic, E Song, XB Gao… - Neuron, 2022 - cell.com
Dysregulation of long interspersed nuclear element 1 (LINE-1, L1), a dominant class of
transposable elements in the human genome, has been linked to neurodegenerative diseases, …

Serum levels of galectin-3: possible association with fibrosis, aberrant angiogenesis, and immune activation in patients with systemic sclerosis

…, S Noda, Y Masui, D Yamada, T Takahashi… - The Journal of …, 2012 - jrheum.org
Objective. Galectin-3 is a multifunctional protein implicated in a variety of biological processes
including fibrosis, angiogenesis, and immune activation, all of which are associated with …

[PDF][PDF] Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

…, AMS Toland, JR Gehlhausen, J Klein, T Takahashi… - Cell, 2022 - cell.com
COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …

[HTML][HTML] Distinguishing features of Long COVID identified through immune profiling

…, T Mao, B Bhattacharjee, T Takahashi… - Nature, 2023 - nature.com
Post-acute infection syndromes may develop after acute viral disease 1 . Infection with
SARS-CoV-2 can result in the development of a post-acute infection syndrome known as long …

[HTML][HTML] Saliva or nasopharyngeal swab specimens for detection of SARS-CoV-2

…, A Park, J Silva, E Song, T Takahashi… - … England Journal of …, 2020 - Mass Medical Soc
Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2 | NEJM Skip to main
content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to …

Donor–acceptor-structured 1, 4-diazatriphenylene derivatives exhibiting thermally activated delayed fluorescence: design and synthesis, photophysical properties and …

T Takahashi, K Shizu, T Yasuda… - … and Technology of …, 2014 - iopscience.iop.org
A new series of luminescent 1, 4-diazatriphenylene (ATP) derivatives with various
peripheral donor units, including phenoxazine, 9, 9-dimethylacridane and 3-(diphenylamino) …