Objective. To analyze specific clinical findings, underlying disorders, treatments, outcomes,
and prognostic factors for reactive hemophagocytic syndrome (RHS) in systemic disease. …

Objective. To report our experience on a multicentre series of 32 patients with either typical
or atypical Cogan's syndrome, to combine our results with a detailed review of the literature, …

Objective: To examine the prevalence and characteristics of patients with reactive
haemophagocytic syndrome (RHS) complicating adult-onset Still’s disease (AOSD). Methods: Of 50 …

Background The combination of cyclophosphamide and glucocorticoids leads to remission
in most patients with antineutrophil cytoplasm antibody (ANCA)–associated vasculitides. …

Background Within a period of three years, we identified 13 patients in whom pure red-cell
aplasia developed during treatment with recombinant human erythropoietin (epoetin). We …

Background Current standard therapy for Wegener's granulomatosis and microscopic
polyangiitis combines corticosteroids and cyclophosphamide to induce remission, followed by a …

… was 24 t 10 years (mean t standard deviation; range, 7–57 yr). Mean age at diagnosis was
27 t 11 years (range, 9–64 yr) and mean age at renal involvement onset was 28 t 11 years (…

There is a significant under-registration of blind and visually impaired patients attending
ophthalmic departments. Blindness is defined by the World Health Organization (WHO) as the …

Whether rituximab could effectively and safely avoid splenectomy for adults with chronic
immune thrombocytopenic purpura (ITP) remains unresolved. A multicenter, prospective, open-…

… analyzed modifications of T-cell subsets in IgG4-RSD. T helper 2 (Th2) and regulatory T cells
were … Other T-cell subsets, such as follicular helper T cells, may certainly participate in the …