Influence of CYP3A5 and ABCB1 gene polymorphisms on calcineurin inhibitor‐related neurotoxicity after hematopoietic stem cell transplantation

M Yanagimachi, T Naruto, R Tanoshima… - Clinical …, 2010 - Wiley Online Library
… It was reported that ABCB1 G2677A/T and ABCB1 C3435T instead of ABCB1 C1236T
were associated with FK506-related neurotoxicity such as convulsion, tremor, or …

Toll‐like receptor 9 plays a pivotal role in angiotensin II–induced atherosclerosis

…, XF Lei, K Masuda, T Naruto… - Journal of the …, 2019 - Am Heart Assoc
… Comparison of parameters between 2 groups was performed with unpaired Student t test
when data showed a normal distribution or with Mann–Whitney U test when data did not show …

[HTML][HTML] Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer

A Hirasawa, I Imoto, T Naruto, T Akahane… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pathogenic germline BRCA1, BRCA2 (BRCA1/2), and several other gene variants predispose
women to primary ovarian, fallopian tube, and peritoneal carcinoma (OC), although …

APRIL-dependent lifelong plasmacyte maintenance and immunoglobulin production in humans

TW Yeh, T Okano, T Naruto, M Yamashita… - Journal of Allergy and …, 2020 - Elsevier
… were determined by using a Student t test or Welch t test. … As he has had no frequent infection,
normal T- and B-cell levels, … T-cell receptor recombination excision circles and signal joint …

Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis

M Yanagimachi, T Naruto, T Miyamae, T Hara… - The Journal of …, 2011 - jrheum.org
… Our investigation revealed that the rs2004640 T allele and the ATT haplotype in the IRF5 …
The T alleles of both rs2004640 and rs2280714 were associated with higher levels of IRF5 …

A CpG-containing oligodeoxynucleotide as an efficient adjuvant counterbalancing the Th1/Th2 immune response in diphtheria–tetanus–pertussis vaccine

T Sugai, M Mori, M Nakazawa, M Ichino, T Naruto… - Vaccine, 2005 - Elsevier
… to influence the differentiation of T lymphocyte responses toward the T helper (Th) 2 … 16],
[17], and one study group reported that CpG induced T-bet (Th1 gene regulator) expression and …

Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis

M Yanagimachi, T Naruto, T Hara… - British journal of …, 2011 - Wiley Online Library
… For continuous predictors, such as age and duration of MTX treatment, Student's unpaired
t-test was used to assess the association between clinical predictors and the toxicity and …

Clinical control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes

…, T Akahoshi, M Koyanagi, T Chikata, T Naruto… - Journal of …, 2015 - Am Soc Microbiol
… Identification and characterization of CD8 + T cells effectively controlling HIV-1 variants are
… + T cells have been only partially identified. In this study, we sought to identify CD8 + T cells …

Autosomal recessive complete STAT1 deficiency caused by compound heterozygous intronic mutations

…, S Kimura, M Tamaura, T Okano, T Naruto… - International …, 2020 - academic.oup.com
T-lymphocyte activation after phytohemagglutinin (PHA) or concanavalin A (ConA) stimulation.
No obvious abnormality was observed in the T- and B-cell counts, with normal results for T

Interleukin-6, interleukin-8, and soluble tumor necrosis factor receptor-I in the cord blood as predictors of chronic lung disease in premature infants

…, A Haruki, T Naruto, N Kobayashi, T Sugai… - American journal of …, 2004 - Elsevier
OBJECTIVES: In order to predict the late-development of chronic lung disease of prematurity
(CLD), cytokines in the cord blood were assessed in this study. STUDY DESIGN: Eighteen …