Background New drugs and new evidence concerning the use of established treatments have
become available since the publication of the first European League Against Rheumatism …

It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level (…

Objectives To agree terminology and to develop recommendations for the diagnosis of calcium
pyrophosphate deposition (CPPD). Methods The European League Against Rheumatism …

Massive Online Analysis (MOA) is a software environment for implementing algorithms and
running experiments for online learning from evolving data streams. MOA is designed to deal …

Background Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and
oxygenation in a patient who does not have spontaneous circulation. The evidence with regard …

… Janssens HJ, Fransen J, van de Lisdonk EH, van Riel PL, van Weel C, Janssen M. A
diagnostic rule for acute gouty arthritis in primary care without joint fluid analysis. Arch Intern Med …

<p id="p001">Mucocutaneous fungal infections are typically found in patients who have no
known immune defects. We describe a family in which four women who were affected by …

Rationale: It is unknown whether lactate monitoring aimed to decrease levels during initial
treatment in critically ill patients improves outcome. Objectives: To assess the effect of lactate …

… Immunological memory in vertebrates is often exclusively attributed to T and B cell function.
… Testing this concept of ‘‘trained immunity,’’ we show that mice lacking functional T and B …

The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer
layer of proteins glycosylated with N-or O-linked mannosyl residues and an inner skeletal …